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@ARTICLE{Kransberg:285920,
      author       = {Kransberg, Jonas and Sjøli Bråthen, Anne Cecilie and
                      Falch, Emilie Sogn and Øverbye, Knut E. Ø. and Garrido,
                      Pablo F. and Fjell, Anders M. and Stangl, Matthias and
                      Wolbers, Thomas and Sneve, Markus H. and Walhovd, Kristine
                      B.},
      title        = {{F}ailure to detect entorhinal grid-like signals in a
                      passive navigation human f{MRI} study},
      journal      = {Imaging neuroscience},
      volume       = {4},
      issn         = {2837-6056},
      address      = {Cambridge, MA},
      publisher    = {MIT Press},
      reportid     = {DZNE-2026-00366},
      pages        = {IMAG.a.1196},
      year         = {2026},
      abstract     = {Grid cells in the human entorhinal cortex (EC) play a
                      critical role in spatial navigation and memory. The EC is
                      also one of the first regions affected by ageing and
                      Alzheimer’s disease. This pre-registered functional
                      magnetic resonance imaging (fMRI) study aimed to detect
                      grid-cell-like signals (GLS) in a passive virtual navigation
                      task. Contrary to our hypotheses and previous findings, we
                      did not observe significant GLS at a population level, even
                      in younger participants. Further exploratory analyses
                      investigated the impact of task-engagement, as inferred from
                      object-location memory performance, and showed no
                      relationship with GLS magnitude. We also examined potential
                      influences of a confounding one-fold directional signal and
                      various data-processing choices but observed no consistent
                      patterns. Our findings, consistent with recent null results
                      from similar studies, suggest that passive navigation
                      paradigms may be insufficient for reliably eliciting
                      grid-like signals in human fMRI.},
      cin          = {AG Wolbers},
      ddc          = {610},
      cid          = {I:(DE-2719)1310002},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.1162/IMAG.a.1196},
      url          = {https://pub.dzne.de/record/285920},
}