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000286087 1001_ $$aNager, Ladina$$b0
000286087 245__ $$aSleep is associated with posttraumatic stress symptom severity in patients with an implantable cardioverter-defibrillator depending on age.
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000286087 520__ $$aPatients with implantable cardioverter-defibrillators (ICDs) are vulnerable to psychological distress, including posttraumatic stress disorder (PTSD). Impaired sleep is a hallmark of PTSD, and may also act as a risk factor that maintains or exacerbates PTSD, yet this relationship has not been examined in ICD recipients across different ages. We assessed 422 patients with ICD or cardiac resynchronisation therapy with defibrillator (CRT-D) who completed the Pittsburgh sleep quality index (PSQI) and post-traumatic diagnostic scale (PDS). 44.2% of patients showed impaired sleep (PSQI > 5). A multiple linear regression model showed that poorer sleep was associated with greater PTSD severity, and this association weakened with increasing age (interaction β = - 0.002, 95% CI [- 0.004, - 0.001], p = 0.008), indicating stronger effects in younger patients. Exploratory component analyses identified daytime dysfunction (β = 0.351, 95% CI [0.212, 0.490], p < 0.001) and sleep disturbance (β = 0.345, 95% CI [0.126, 0.564], p = 0.002) as the components most strongly linked to PTSD symptoms. These findings support that routine sleep screening is an important component of comprehensive ICD care, identifying clinically relevant sleep disturbance associated with PTSD symptom severity and underscoring sleep as a meaningful and modifiable treatment target.
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000286087 650_7 $$2Other$$aAge
000286087 650_7 $$2Other$$aImplantable cardioverter-defibrillator (ICD)
000286087 650_7 $$2Other$$aPittsburgh sleep quality index (PSQI)
000286087 650_7 $$2Other$$aPosttraumatic stress disorder (PTSD)
000286087 650_7 $$2Other$$aSleep
000286087 650_2 $$2MeSH$$aHumans
000286087 650_2 $$2MeSH$$aStress Disorders, Post-Traumatic: etiology
000286087 650_2 $$2MeSH$$aStress Disorders, Post-Traumatic: physiopathology
000286087 650_2 $$2MeSH$$aDefibrillators, Implantable: psychology
000286087 650_2 $$2MeSH$$aDefibrillators, Implantable: adverse effects
000286087 650_2 $$2MeSH$$aMale
000286087 650_2 $$2MeSH$$aFemale
000286087 650_2 $$2MeSH$$aMiddle Aged
000286087 650_2 $$2MeSH$$aAged
000286087 650_2 $$2MeSH$$aSleep Wake Disorders
000286087 650_2 $$2MeSH$$aSeverity of Illness Index
000286087 650_2 $$2MeSH$$aAge Factors
000286087 650_2 $$2MeSH$$aSleep: physiology
000286087 650_2 $$2MeSH$$aAdult
000286087 650_2 $$2MeSH$$aRisk Factors
000286087 650_2 $$2MeSH$$aSleep Quality
000286087 7001_ $$aPrincip, Mary$$b1
000286087 7001_ $$aAttanasio, Veronica$$b2
000286087 7001_ $$0P:(DE-2719)9002951$$aDörner, Marc$$b3$$udzne
000286087 7001_ $$aGuth, Lisa$$b4
000286087 7001_ $$aZirngast, Sina$$b5
000286087 7001_ $$aSila, Rahel$$b6
000286087 7001_ $$aPazhenkottil, Aju P$$b7
000286087 7001_ $$aMenzi, Anna$$b8
000286087 7001_ $$aKönig, Noelle$$b9
000286087 7001_ $$aZuccarella-Hackl, Claudia$$b10
000286087 7001_ $$avon Känel, Roland$$b11
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