Review

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2022-11-23
12:09
OpenAccess [DZNE-2022-01671] Review/Journal Article
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Molecular disease mechanisms of human antineuronal monoclonal autoantibodies.
Autoantibodies targeting brain antigens can mediate a wide range of neurological symptoms ranging from epileptic seizures to psychosis to dementia. Although earlier experimental work indicated that autoantibodies can be directly pathogenic, detailed studies on disease mechanisms, biophysical autoantibody properties, and target interactions were hampered by the availability of human material and the paucity of monospecific disease-related autoantibodies. [...]
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2022-11-21
12:33
OpenAccess [DZNE-2022-01660] Review/Journal Article
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Overview Article Astrocytes as Initiators of Epilepsy.
Neurochemical research Advance online publication, n/a () [10.1007/s11064-022-03773-z]
Astrocytes play a dual role in the brain. On the one hand, they are active signaling partners of neurons and can for instance control synaptic transmission and its plasticity. [...]
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2022-07-12
10:34
[DZNE-2022-01298] Review/Journal Article
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Primär progrediente Aphasie (PPA): Begriffsdefinition und Spektrum an Subtypen
Sprache, Stimme, Gehör 45(04), 173 - 178 () [10.1055/a-1557-8330]
Die primär progrediente Aphasie (PPA) ist ein Sammelbegriff für Demenzformen, die sich durch Defizite in verschiedenen Aspekten der Sprache, z. B. im Sprachverständnis, kennzeichnen. [...]

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