AG Latz

⇧ BN DZNE ⇧

Recent Publications

All known publications ...
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http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Feng, R. (First author)DZNE* ; Spieth, L.DZNE* ; Liu, L.DZNE* ; Berghoff, S.DZNE* ; Franz, J. ; Liu, Q.DZNE* ; Wang, Z.DZNE* ; Tiwari, V.DZNE* ; Vitale, S.DZNE* ; Frerich, S. ; Florensa, S.DZNE* ; Junker, N.DZNE* ; Huber, L.DZNE* ; Keller, M. ; Müller, C. ; Bracher, F. ; Ge, X. ; Rensen, P. C. N. ; Kooij, G. ; Hosang, L. ; Chornyi, S. ; Dichgans, M.DZNE* ; Gokce, O.DZNE* ; Saher, G. ; Stadelmann, C. ; Giera, M. ; Groh, J.DZNE* ; Simons, M. (Last author)DZNE*
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
Immunity 58(12), 2989 - 3005.e10 (2025) [10.1016/j.immuni.2025.10.003]2025   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Ravichandran, K. A. (First author)DZNE* ; Brosseron, F.DZNE* ; McManus, R. M.DZNE* ; Ising, C. ; Görgen, S. ; Schmidt, S. V. ; Santarelli, F. ; Lee, S. Y. ; Jung, H. ; Chung, W.-S. ; Kim, C. H. ; Ruiz Laza, A. ; Ruiz de Almodóvar, C. ; Ramirez, A.Extern* ; Latz, E.DZNE* ; Heneka, M. T. (Last author)DZNE*
Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models.
Journal of leukocyte biology 117(12), qiaf157 (2025) [10.1093/jleuko/qiaf157]2025   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dataset Liu, Q.DZNE*
Dataset: Molecular and spatial profiling of multiple sclerosis lesions identifies dysfunctional lipid efflux as a driver of chronic active inflammation
Gene Expression Omnibus (2025)2025   Fulltext BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Erlitz, K. S. ; Prinz, A.-K. ; Wagner, S. ; Massa, J. ; Dunker, C. ; Höhl, M. ; Griep, A.DZNE* ; McManus, R. M.DZNE* ; Schelhaas, S. ; Koch, O. ; Junker, A.
Naphtho[1,2-b][1,4]diazepinedione-Based P2X4 Receptor Antagonists from Structure-Activity Relationship Studies toward PET Tracer Development.
Journal of medicinal chemistry 68(7), 6965 - 7002 (2025) [10.1021/acs.jmedchem.4c02171]2025   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article McManus, R. M. (First author)DZNE* ; Komes, M.DZNE* ; Griep, A.DZNE* ; Santarelli, F.DZNE* ; Schwartz, S. ; Perea, J. R.DZNE* ; Schlachetzki, J. C. M. ; Bouvier, D. S. ; Khalil, M.-A. ; Lauterbach, M. A.DZNE* ; Heinemann, L.DZNE* ; Schlüter, T.DZNE* ; Pour, M. S.DZNE* ; Lovotti, M. ; Stahl, R. ; Duthie, F. ; Rodríguez-Alcázar, J. F. ; Schmidt, S. V. ; Spitzer, J. ; Noori, P. ; Maillo, A. ; Boettcher, A. ; Herron, B. ; McConville, J. ; Gomez-Cabrero, D. ; Tegnér, J. ; Glass, C. K. ; Hiller, K. ; Latz, E. (Last author)DZNE* ; Heneka, M. (Last author)DZNE*
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
Immunity 58(2), 326 - 343.e11 (2025) [10.1016/j.immuni.2025.01.007]2025   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Wang, W. ; Dernst, A. ; Martin, B. ; Lorenzi, L. ; Cadefau-Fabregat, M. ; Phulphagar, K. ; Wagener, A. ; Budden, C. ; Stair, N. ; Wagner, T. ; Färber, H. ; Jaensch, A. ; Stahl, R. ; Duthie, F. ; Schmidt, S. V. ; Coll, R. C. ; Meissner, F. ; Cuartero, S. ; Latz, E.DZNE* ; Mangan, M. (Last author)DZNE*
Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.
Cell reports 43(9), 114736 (2024) [10.1016/j.celrep.2024.114736]2024   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Scheiblich, H. (First author)DZNE* ; Eikens, F.DZNE* ; Wischhof, L.DZNE* ; Opitz, S. ; Jüngling, K. ; Cserép, C. ; Schmidt, S. V. ; Lambertz, J. ; Bellande, T. ; Pósfai, B. ; Geck, C. ; Spitzer, J. ; Odainic, A. ; Castro-Gomez, M. S.Extern* ; Schwartz, S. ; Boussaad, I. ; Krüger, R. ; Glaab, E. ; Di Monte, D. A.DZNE* ; Bano, D.DZNE* ; Dénes, Á. ; Latz, E.DZNE* ; Melki, R. ; Pape, H.-C. ; Heneka, M. T. (Last author)DZNE*
Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.
Neuron 112(18), 3106 - 3125.e8 (2024) [10.1016/j.neuron.2024.06.029]2024   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Editorial) Shi, Y. ; Strasser, A. ; Green, D. R. ; Latz, E.DZNE* ; Mantovani, A. ; Melino, G.Extern*
Legacy of the discovery of the T-cell receptor: 40 years of shaping basic immunology and translational work to develop novel therapies.
Cellular & molecular immunology 21(7), 790 - 797 (2024) [10.1038/s41423-024-01168-4]2024   Files  Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) McManus, R. M. (First author)DZNE* ; Latz, E.Extern*
NLRP3 inflammasome signalling in Alzheimer's disease
Neuropharmacology 252, 109941 (2024) [10.1016/j.neuropharm.2024.109941]2024   Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Wolf, C. ; Lim, E. L. ; Mokhtari, M. ; Kind, B. ; Odainic, A. ; Lara-Villacanas, E. ; Koss, S. ; Mages, S. ; Menzel, K. ; Engel, K. ; Dückers, G. ; Bernbeck, B. ; Schneider, D. T. ; Siepermann, K. ; Niehues, T. ; Goetzke, C. C. ; Durek, P. ; Minden, K. ; Dörner, T. ; Stittrich, A. ; Szelinski, F. ; Guerra, G. M. ; Massoud, M. ; Bieringer, M. ; de Oliveira Mann, C. C. ; Beltrán, E. ; Kallinich, T. ; Mashreghi, M.-F. ; Schmidt, S. V. ; Latz, E.DZNE* ; Klughammer, J. ; Majer, O. ; Lee-Kirsch, M. A.
UNC93B1 variants underlie TLR7-dependent autoimmunity.
Science immunology 9(92), eadi9769 (2024) [10.1126/sciimmunol.adi9769]2024   Files BibTeX | EndNote: XML, Text | RIS

All known publications ...
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