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AG Latz
Innate Immunity in Neurodegeneration Also known as:AG Latz; Angeborene Immunität bei Neurodegeneration; Angeborene Immunität in Neurodegeneration| ID | I:(DE-2719)1013024 |
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Journal Article
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
Immunity 58(12), 2989 - 3005.e10 (2025) [10.1016/j.immuni.2025.10.003]
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Journal Article
Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models.
Journal of leukocyte biology 117(12), qiaf157 (2025) [10.1093/jleuko/qiaf157]
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Dataset
Dataset: Molecular and spatial profiling of multiple sclerosis lesions identifies dysfunctional lipid efflux as a driver of chronic active inflammation
Gene Expression Omnibus (2025)
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Journal Article
Naphtho[1,2-b][1,4]diazepinedione-Based P2X4 Receptor Antagonists from Structure-Activity Relationship Studies toward PET Tracer Development.
Journal of medicinal chemistry 68(7), 6965 - 7002 (2025) [10.1021/acs.jmedchem.4c02171]
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Journal Article
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
Immunity 58(2), 326 - 343.e11 (2025) [10.1016/j.immuni.2025.01.007]
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Journal Article
Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.
Neuron 112(18), 3106 - 3125.e8 (2024) [10.1016/j.neuron.2024.06.029]
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Journal Article
UNC93B1 variants underlie TLR7-dependent autoimmunity.
Science immunology 9(92), eadi9769 (2024) [10.1126/sciimmunol.adi9769]
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Journal Article
Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.
Cell reports 43(9), 114736 (2024) [10.1016/j.celrep.2024.114736]
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Contribution to a book
Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation.
Tissue-Resident Macrophages / Mass, Elvira (Editor) ; New York, NY : Springer US, 2024, Chapter 29 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-0716-3436-3=978-1-0716-3437-0 ; doi:10.1007/978-1-0716-3437-0
New York, NY : Springer US, Methods in Molecular Biology 2713, 431 - 451 (2024) [10.1007/978-1-0716-3437-0_29]
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Contribution to a book
Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation.
Tissue-Resident Macrophages / Mass, Elvira (Editor) ; New York, NY : Springer US, 2024, Chapter 28 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-0716-3436-3=978-1-0716-3437-0 ; doi:10.1007/978-1-0716-3437-0
New York, NY : Springer US, Methods in Molecular Biology 2713, 407 - 429 (2024) [10.1007/978-1-0716-3437-0_28]
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All known publications ...
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