AG Wurst

Genome Engineering Also known as:AG Wurst; Genom Engineering; Genom-Engineering Einheit
IDI:(DE-2719)1140001

M DZNE

Recent Publications

All known publications ...
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TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.
Nature Communications 17(1), 2002 () [10.1038/s41467-026-68706-8] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1-linked Parkinson's neurons.
Science advances 12(7), eadz5645 () [10.1126/sciadv.adz5645] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The Absence of Claudin-10 in the Enamel Organ Alters Its Integrity.
Journal of dental research 105(3), 385 - 395 () [10.1177/00220345251349109] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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BACE1 regulates sleep–wake cycle through both enzymatic and non–enzymatic actions
EMBO reports 27, 50 - 68 () [10.1038/s44319-025-00604-4] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs.
Nature immunology 26(12), 2227 - 2243 () [10.1038/s41590-025-02325-1]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Establishment and behavioural characterization of a novel constitutive P2X7 receptor knockout mouse line.
Purinergic signalling 21(5), 1077 - 1092 () [10.1007/s11302-025-10074-x] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Neuropathy-associated Tecpr2 mutation knock-in mice reveal endolysosomal loss of function phenotypes in neurons and microglia.
Cell death & disease 16(1), 775 () [10.1038/s41419-025-08168-w] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes.
Investigative ophthalmology & visual science 66(6), 64 () [10.1167/iovs.66.6.64] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Pervasive glycative stress links metabolic imbalance and muscle atrophy in early-onset Parkinson's disease.
Molecular metabolism 97, 102163 () [10.1016/j.molmet.2025.102163] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis.
Immunity 58(3), 555 - 567.e9 () [10.1016/j.immuni.2025.01.003] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

All known publications ...
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 Record created 2020-02-18, last modified 2024-08-16



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