AG Wegmann
Protein Actions in Neurodegeneration
Also known as:AG Wegmann; Proteinprozesse in Neurodegeneration; Proteinprozesse in der Neurodegeneration
⇧ B DZNE ⇧
Recent Publications
All known publications ...
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Journal Article
Sporbeck, K. (First author)DZNE* ; Ghosh, S. ; Sankar, R.DZNE* ; Nagy-Herczeg, B. K.DZNE* ; Wegmann, S.DZNE* ; Agudo-Canalejo, J. ; Knorr, R. L.
Novel Analysis Method for Condensate Wetting Identifies Charge-Dependent Tau-Membrane Interactions
PRX life 4(3), 033014 (2026) [10.1103/8x47-4t2b]2026
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Journal Article
Askin, B. (First author)DZNE* ; Kilic, C.DZNE* ; Cordero Gómez, C.DZNE* ; Duong, S. L.DZNE* ; Domingues-Baquero, A.DZNE* ; Goihl, A. ; Nalbach, K.DZNE* ; Petushi, J.DZNE* ; Grundschöttel, P.DZNE* ; Wagner, J.DZNE* ; Thomas, V.DZNE* ; Lamberty, J.DZNE* ; Withers, E.DZNE* ; Huber, H.DZNE* ; Hübschmann, S.DZNE* ; Semenova, E.DZNE* ; Turko, P. ; Newman, A. G. ; Diez, L.DZNE* ; Beyer, M.DZNE* ; De Domenico, E.DZNE* ; Körtvelyessy, P.DZNE* ; Reinhold, D. ; Schneider, A.DZNE* ; Neher, J. J.DZNE* ; Ulas, T.DZNE* ; Lichtenthaler, S. F.DZNE* ; Rost, B. R.DZNE* ; Schmitz, D.DZNE* ; Prüss, H.DZNE* ; Wegmann, S. (Last author)DZNE*
IgLON5 autoimmune antibodies activate Tau via neuronal hyperactivity.
Science advances 12(20), eaec2042 (2026) [10.1126/sciadv.aec2042]2026
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Journal Article
McGurran, H. ; Graceffo, E. ; Kumbol, V. ; Jendrach, M. ; Hinkelmann, L. ; Brehm, M. ; Ravatt, L.DZNE* ; Krüger, C. ; Wallach, T. ; Haake, A.DZNE* ; Wegmann, S.DZNE* ; Heppner, F. L.DZNE* ; Schülke, M. ; Lehnardt, S.
MicroRNA-29a-5p contributes to neuroinflammation through TLR7.
Journal of neuroinflammation 23(1), 38 (2026) [10.1186/s12974-025-03680-4]2026
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Journal Article
Simonetti, F. (First author)DZNE* ; Zhong, W. ; Hutten, S. ; Uliana, F. ; Schifferer, M.DZNE* ; Rezaei, A.DZNE* ; Ramirez, L. M.DZNE* ; Hochmair, J.DZNE* ; Sankar, R.DZNE* ; Gopalan, A. ; Kielisch, F. ; Riemenschneider, H.DZNE* ; Ruf, V. ; Schmidt, C. ; Simons, M.DZNE* ; Zweckstetter, M.DZNE* ; Wegmann, S.DZNE* ; Lashley, T. ; Polymenidou, M. ; Edbauer, D.DZNE* ; Dormann, D.
Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding.
The EMBO journal 44(24), 7395 - 7433 (2025) [10.1038/s44318-025-00590-2]2025
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Journal Article (Editorial)
Alberti, S. ; Arosio, P. ; Best, R. B. ; Boeynaems, S. ; Cai, D. ; Collepardo-Guevara, R. ; Dignon, G. L. ; Dimova, R. ; Elbaum-Garfinkle, S. ; Fawzi, N. L. ; Fuxreiter, M. ; Gladfelter, A. S. ; Honigmann, A. ; Jain, A. ; Joseph, J. A. ; Knowles, T. P. J. ; Lasker, K. ; Lemke, E. A. ; Lindorff-Larsen, K. ; Lipowsky, R. ; Mittal, J. ; Mukhopadhyay, S. ; Myong, S. ; Pappu, R. V. ; Rippe, K. ; Shelkovnikova, T. A. ; Vecchiarelli, A. G. ; Wegmann, S.DZNE* ; Zhang, H. ; Zhang, M. ; Zubieta, C. ; Zweckstetter, M.DZNE* ; Dormann, D. ; Mittag, T.
Current practices in the study of biomolecular condensates: a community comment.
Nature Communications 16(1), 7730 (2025) [10.1038/s41467-025-62055-8]2025
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Journal Article
Hochmair, J. (First author)DZNE* ; van den Oetelaar, M. C. M. ; Ravatt, L.DZNE* ; Diez, L.DZNE* ; Lemmens, L. J. M. ; Ponce-Lina, R. ; Sankar, R.DZNE* ; Franck, M.DZNE* ; Nolte, G.DZNE* ; Semenova, E.DZNE* ; Mohapatra, S.DZNE* ; Ottmann, C. ; Brunsveld, L. ; Wegmann, S. (Last author)DZNE*
Stoichiometric 14-3-3ζ binding promotes phospho-Tau microtubule dissociation and reduces aggregation and condensation.
Communications biology 8(1), 1139 (2025) [10.1038/s42003-025-08548-0]2025
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Journal Article (Review Article)
Frost, B. ; Rowe, J. B. ; Akinyemi, R. O. ; Abisambra, J. F. ; Ashton, N. J. ; Brendel, M.DZNE* ; Buée, L. ; Butler, D. ; Carrillo, M. C. ; Chung, P. ; Clelland, C. D. ; DeVos, S. L. ; Diaz, K. ; Edelmayer, R. M. ; Elahi, F. M. ; Ellajosyula, R. ; Ewen, C. ; Fontana, I. C. ; Galas, M.-C. ; Hansson, O. ; Höglinger, G.DZNE* ; Horie, K. ; Ibanez, A. ; Jacobs, L. ; Maina, M. B. ; Malpetti, M. ; McDade, E. ; McEwan, W. ; Montoliu-Gaya, L. ; Mummery, C. J. ; Orr, M. E. ; Rohrer, J. D. ; Rommel, A. ; Sastre, C. ; Spires-Jones, T. L. ; Tee, B. L. ; Viney, T. J. ; Walker, J. M. ; Wegmann, S.DZNE* ; Wildsmith, K. ; Yadav, R. ; Mahinrad, S. ; Sexton, C.
Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.
Alzheimer's and dementia 21(5), e70078 (2025) [10.1002/alz.70078]2025
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Journal Article
Amaral, M.Extern* ; Passos, A. R. ; Mohapatra, S.DZNE* ; Freire, M. H. ; Wegmann, S.DZNE* ; Cordeiro, Y.
X-Ray Photon Correlation Spectroscopy, Microscopy, and Fluorescence Recovery After Photobleaching to Study Phase Separation and Liquid-to-Solid Transition of Prion Protein Condensates.
Bio-protocol 15(8), e5277 (2025) [10.21769/BioProtoc.5277]2025
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Journal Article/Contribution to a conference proceedings
Deckert, A. ; Böddrich, A. ; Diez, L.DZNE* ; Schmitt, M. J. ; Nevado, J. C. C. ; Beetz, S. ; Brusendorf, L. ; Serresi, M. ; Wegmann, S.DZNE* ; Gargiulo, G. ; Wanker, E.
Unraveling the interplay between tau seeding and autophagy processes
2024Alzheimer's Association International Conference, AAIC 2024, PhiladelphiaPhiladelphia, USA, 28 Jul 2024 - 1 Aug 20242024-07-282024-08-01
Alzheimer's and dementia 20(S1), e089660 (2024) [10.1002/alz.089660]2024
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Journal Article (Review Article)
Basheer, N. ; Buee, L. ; Brion, J.-P. ; Smolek, T. ; Muhammadi, M. K. ; Hritz, J. ; Hromadka, T. ; Dewachter, I. ; Wegmann, S.DZNE* ; Landrieu, I. ; Novak, P. ; Mudher, A. ; Zilka, N.
Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models.
Acta Neuropathologica Communications 12(1), 52 (2024) [10.1186/s40478-024-01748-5]2024
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All known publications ...
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