AG Heppner
Neuroimmunology
Also known as:AG Heppner; Neuroimmunologie
⇧ B DZNE ⇧
Recent Publications
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Ovesen, P. L. ; Juul-Madsen, K. ; Telugu, N. S. ; Schmidt, V. ; Frahm, S. ; Radbruch, H. ; Louth, E. L. ; Korshøj, A. R. ; Heppner, F. L.DZNE* ; Diecke, S. ; Kettenmann, H. ; Willnow, T. E.
Alzheimer's Disease Risk Gene SORL1 Promotes Receptiveness of Human Microglia to Pro-Inflammatory Stimuli.
Glia 73(4), 857 - 872 (2025) [10.1002/glia.24659]2025
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Hubertus, V. ; Meyer, L. ; Waldmann, L. ; Roolfs, L. ; Taheri, N. ; Kersting, K. ; von Bronewski, E. ; Nieminen-Kelhä, M. ; Kremenetskaia, I. ; Uhl, C. ; Fiedler, K. C. ; Ode, J.-E. ; Rex, A. ; Prüß, H.DZNE* ; Rakhymzhan, A. ; Hauser, A. E. ; Niesner, R. ; Heppner, F. L.DZNE* ; Fehlings, M. G. ; Vajkoczy, P.
Identification of a Therapeutic Window for Neurovascular Unit Repair after Experimental Spinal Cord Injury.
Journal of neurotrauma 42(3-4), 212 - 228 (2025) [10.1089/neu.2024.0233]2025
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Woo, M. S. ; Brand, J. ; Bal, L. C. ; Moritz, M. ; Walkenhorst, M. ; Vieira, V. ; Ipenberg, I. ; Rothammer, N. ; Wang, M. ; Dogan, B. ; Loreth, D. ; Mayer, C. ; Nagel, D. ; Wagner, I. ; Pfeffer, L. K. ; Landgraf, P. ; van Ham, M. ; Mattern, K. M. ; Winschel, I. ; Frantz, N. ; Sonner, J. K. ; Grosshans, H. K. ; Miguela, A. ; Bauer, S. ; Meurs, N. ; Müller, A. ; Binkle-Ladisch, L. ; Salinas, G. ; Jänsch, L. ; Dieterich, D. C. ; Riedner, M. ; Krüger, E. ; Heppner, F. L.DZNE* ; Glatzel, M. ; Puelles, V. G. ; Engler, J. B. ; Nyengaard, J. R. ; Misgeld, T.DZNE* ; Kerschensteiner, M. ; Merkler, D. ; Meyer-Schwesinger, C. ; Friese, M. A.
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis.
Cell 188(17), 4567 - 4585.e32 (2025) [10.1016/j.cell.2025.05.029]2025
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Krech, M. ; Muench, A. ; Teichmann, D. ; Kuzman, P. ; Suwala, A. K. ; Ippen, F. M. ; Müther, M. ; Weber, K. J. ; Wenger-Alakmeh, K. ; Onken, J. ; Vajkoczy, P. ; Behling, F. ; May, S.-A. ; Ntoulias, G. ; Krauss, J. K. ; Atallah, O. ; Esmaeilzadeh, M. ; Mueller, W. C. ; Heppner, F. L.DZNE* ; Radbruch, H. ; Dittmayer, C. ; Stenzel, W. ; Koch, A. ; Capper, D. ; Kaul, D. ; Paulus, W. ; Plate, K. H. ; Steinbach, J. P. ; Czabanka, M. ; Beschorner, R. ; von Deimling, A. ; Bockmayr, M. ; Neumann, J. E. ; Brandner, S. ; Krieger, T. ; Hartmann, C. ; Thomas, C. ; Schweizer, L.
Outcome-associated factors in a molecularly defined cohort of central neurocytoma.
Acta neuropathologica 149(1), 61 (2025) [10.1007/s00401-025-02894-3]2025
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Schneeberger, S. ; Kim, S. J. ; Geesdorf, M. N. ; Friebel, E.Extern* ; Eede, P. ; Jendrach, M. ; Boltengagen, A. ; Braeuning, C. ; Ruhwedel, T. ; Hülsmeier, A. J. ; Gimber, N. ; Foerster, M. ; Obst, J. ; Andreadou, M. ; Mundt, S. ; Schmoranzer, J. ; Prokop, S. ; Kessler, W. ; Kuhlmann, T. ; Möbius, W. ; Nave, K.-A. ; Hornemann, T. ; Becher, B. ; Edgar, J. M. ; Karaiskos, N. ; Kocks, C. ; Rajewsky, N. ; Heppner, F. L. (Last author)DZNE*
Interleukin-12 signaling drives Alzheimer's disease pathology through disrupting neuronal and oligodendrocyte homeostasis.
Nature aging 5(4), 622 - 641 (2025) [10.1038/s43587-025-00816-2]2025
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Moser, I. ; Engelhardt, M. ; Grittner, U. ; Ferreira, F. M. S. R. ; Denker, M. ; Reinsch, J. ; Fischer, L. ; Link, T. ; Heppner, F. L.DZNE* ; Capper, D. ; Vajkoczy, P. ; Picht, T. ; Rosenstock, T.
Analysis of Neuronal Excitability Profiles for Motor-Eloquent Brain Tumor Entities Using nTMS in 800 Patients.
Cancers 17(6), 935 (2025) [10.3390/cancers17060935] special issue: "Surgical Advances in the Treatment of Gliomas: Preserving Function and Quality of Life"2025
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Entenmann, C. J. ; von Bronewski, E. J. ; Waldmann, L. ; Meyer, L. ; Kersting, K. ; Roolfs, L. T. ; Schleker, L. M. ; Nieminen-Kelhä, M. ; Kremenetskaia, I. ; Heppner, F. L.DZNE* ; Fehlings, M. G. ; Vajkoczy, P. ; Hubertus, V.
Analysis of the spatiotemporal dynamics of vascular injury and regeneration following experimental Spinal Cord Injury.
Brain and spine 5, 104191 (2025) [10.1016/j.bas.2025.104191]2025
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Drude, N. ; Diederich, K. ; Duerr, C. U. ; Haase, N. ; Harms, C. ; Heppner, F.DZNE* ; Jendrach, M.DZNE* ; Kahnau, P. ; Kolesnichenko, M. ; Lewejohann, L. ; Kurreck, C. ; Lohan, A. ; Mall, M. A. ; Müller, D. ; Nagel-Riedasch, S. ; Opitz, B. ; Schaupp, L. ; Schönfelder, G. ; Weber, A. ; Willimsky, G. ; Zang, Y. ; Rosshart, S. P. ; Diefenbach, A. ; Jordan, S.
Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
JoVE science education Immunology and Infection(214), 67100 (2024) [10.3791/67100]2024
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Rifat, A. ; Ossola, B. ; Bürli, R. W. ; Dawson, L. A. ; Brice, N. L. ; Rowland, A. ; Lizio, M. ; Xu, X. ; Page, K. ; Fidzinski, P. ; Onken, J. ; Holtkamp, M. ; Heppner, F. L.DZNE* ; Geiger, J. R. P. ; Madry, C.
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia.
Journal of neuroinflammation 21(1), 58 (2024) [10.1186/s12974-024-03042-6]2024
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Radke, J. ; Meinhardt, J. ; Aschman, T. ; Chua, R. L. ; Farztdinov, V. ; Lukassen, S. ; Ten, F. W. ; Friebel, E.Extern* ; Ishaque, N. ; Franz, J. ; Huhle, V. H. ; Mothes, R. ; Peters, K. ; Thomas, C. ; Schneeberger, S. ; Schumann, E. ; Kawelke, L. ; Jünger, J. ; Horst, V. ; Streit, S. ; von Manitius, R. ; Körtvelyessy, P.Extern* ; Vielhaber, S.Extern* ; Reinhold, D. ; Hauser, A. E. ; Osterloh, A. ; Enghard, P. ; Ihlow, J. ; Elezkurtaj, S. ; Horst, D. ; Kurth, F. ; Müller, M. A. ; Gassen, N. C. ; Melchert, J. ; Jechow, K. ; Timmermann, B. ; Fernandez-Zapata, C. ; Böttcher, C. ; Stenzel, W. ; Krüger, E. ; Landthaler, M. ; Wyler, E. ; Corman, V.Extern* ; Stadelmann, C. ; Ralser, M. ; Eils, R. ; Heppner, F. L.DZNE* ; Mülleder, M. ; Conrad, C. ; Radbruch, H.
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Nature neuroscience 27(3), 409 - 420 (2024) [10.1038/s41593-024-01573-y]2024
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