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005     20240321220236.0
024 7 _ |a 10.1212/WNL.0000000000000271
|2 doi
024 7 _ |a pmid:24574548
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024 7 _ |a 0028-3878
|2 ISSN
024 7 _ |a 1526-632X
|2 ISSN
024 7 _ |a altmetric:2230983
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037 _ _ |a DZNE-2020-03715
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Sajjadi, Seyed Ahmad
|0 P:(DE-HGF)0
|b 0
245 _ _ |a Logopenic, mixed, or Alzheimer-related aphasia?
260 _ _ |a [S.l.]
|c 2014
|b Ovid
264 _ 1 |3 online
|2 Crossref
|b Ovid Technologies (Wolters Kluwer Health)
|c 2014-02-26
264 _ 1 |3 print
|2 Crossref
|b Ovid Technologies (Wolters Kluwer Health)
|c 2014-04-01
336 7 _ |a article
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336 7 _ |a ARTICLE
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336 7 _ |a Journal Article
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520 _ _ |a This study tested the hypothesis that patients with primary progressive aphasia (PPA) who do not meet the proposed criteria for any of the recognized subtypes would have the atrophy pattern reported in the past for logopenic variant PPA (lvPPA), in turn suggesting that the PPA of likely Alzheimer disease origin is more variable than that captured in the current lvPPA diagnostic recommendations.MRI gray matter volumes from 14 patients with mixed PPA who failed to meet the diagnostic recommendations for any recognized variant were compared with those of 25 matched control participants via voxel-based morphometry.The mixed PPA group had left temporoparietal atrophy with a pattern identical to that in previously reported lvPPA cohorts.Patients with PPA who did not meet the criteria for any recognized PPA variant at their initial assessment had the group-level atrophy pattern previously reported as the hallmark of lvPPA. We suggest that the specific language features proposed for lvPPA are too narrow to characterize the language impairments arising from likely Alzheimer pathology.
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650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Aged, 80 and over
|2 MeSH
650 _ 2 |a Alzheimer Disease: diagnosis
|2 MeSH
650 _ 2 |a Alzheimer Disease: psychology
|2 MeSH
650 _ 2 |a Aphasia, Primary Progressive: diagnosis
|2 MeSH
650 _ 2 |a Aphasia, Primary Progressive: psychology
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Language Tests: standards
|2 MeSH
650 _ 2 |a Magnetic Resonance Imaging: standards
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Neuropsychological Tests: standards
|2 MeSH
700 1 _ |a Patterson, Karalyn
|0 P:(DE-HGF)0
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700 1 _ |a Nestor, Peter John
|0 P:(DE-2719)2810673
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|e Last author
773 1 8 |a 10.1212/wnl.0000000000000271
|b : Ovid Technologies (Wolters Kluwer Health), 2014-02-26
|n 13
|p 1127-1131
|3 journal-article
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|t Neurology
|v 82
|y 2014
|x 0028-3878
773 _ _ |a 10.1212/WNL.0000000000000271
|g Vol. 82, no. 13, p. 1127 - 1131
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|q 82:13<1127 - 1131
|p 1127-1131
|t Neurology
|v 82
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|x 0028-3878
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|o oai:pub.dzne.de:137393
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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913 1 _ |a DE-HGF
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