Journal Article DZNE-2020-03970

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A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease.

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2014
Elsevier Amsterdam [u.a.]

Alzheimer's and dementia 10(6), 844-852 () [10.1016/j.jalz.2014.01.001]

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Abstract: There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD plus.

Keyword(s): Age of Onset (MeSH) ; Alzheimer Disease: physiopathology (MeSH) ; Cognition Disorders: diagnosis (MeSH) ; Cognition Disorders: physiopathology (MeSH) ; Disease Progression (MeSH) ; Female (MeSH) ; Humans (MeSH) ; Male (MeSH) ; Neuropsychological Tests (MeSH) ; Prodromal Symptoms (MeSH) ; Psychiatric Status Rating Scales (MeSH) ; Terminology as Topic (MeSH)

Classification:

Contributing Institute(s):
  1. Clinical Alzheimer’s Disease Research (AG Jessen)
  2. Population Health Sciences (AG Breteler)
  3. Neuropsychology (AG Wagner)
Research Program(s):
  1. 344 - Clinical and Health Care Research (POF3-344) (POF3-344)
  2. 345 - Population Studies and Genetics (POF3-345) (POF3-345)

Appears in the scientific report 2014
Database coverage:
Medline ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; IF >= 10 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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The record appears in these collections:
Document types > Articles > Journal Article
Institute Collections > BN DZNE > BN DZNE-AG Breteler
Institute Collections > BN DZNE > BN DZNE-AG Jessen
Institute Collections > BN DZNE > BN DZNE-AG Wagner
Public records
Publications Database

 Record created 2020-02-18, last modified 2024-03-21


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