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| 001 | 138492 | ||
| 005 | 20240525120341.0 | ||
| 024 | 7 | _ | |a 10.7554/eLife.09693 |2 doi |
| 024 | 7 | _ | |a pmid:26623514 |2 pmid |
| 024 | 7 | _ | |a pmc:PMC4733035 |2 pmc |
| 024 | 7 | _ | |a altmetric:4832063 |2 altmetric |
| 037 | _ | _ | |a DZNE-2020-04814 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 600 |
| 100 | 1 | _ | |a Farrow, Paul |0 P:(DE-2719)2810462 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties. |
| 260 | _ | _ | |a Cambridge |c 2015 |b eLife Sciences Publications |
| 264 | _ | 1 | |3 online |2 Crossref |b eLife Sciences Publications, Ltd |c 2015-12-01 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1716554237_5214 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a AMPA receptor (AMPAR) function is modulated by auxiliary subunits. Here, we report on three AMPAR interacting proteins-namely CKAMP39, CKAMP52 and CKAMP59-that, together with the previously characterized CKAMP44, constitute a novel family of auxiliary subunits distinct from other families of AMPAR interacting proteins. The new members of the CKAMP family display distinct regional and developmental expression profiles in the mouse brain. Notably, despite their structural similarities they exert diverse modulation on AMPAR gating by influencing deactivation, desensitization and recovery from desensitization, as well as glutamate and cyclothiazide potency to AMPARs. This study indicates that AMPAR function is very precisely controlled by the cell-type specific expression of the CKAMP family members. |
| 536 | _ | _ | |a 341 - Molecular Signaling (POF3-341) |0 G:(DE-HGF)POF3-341 |c POF3-341 |f POF III |x 0 |
| 542 | _ | _ | |i 2015-12-01 |2 Crossref |u http://creativecommons.org/licenses/by/4.0/ |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 650 | _ | 7 | |a Benzothiadiazines |2 NLM Chemicals |
| 650 | _ | 7 | |a CKAMP39 protein, mouse |2 NLM Chemicals |
| 650 | _ | 7 | |a CKAMP52 protein, mouse |2 NLM Chemicals |
| 650 | _ | 7 | |a CKAMP59 protein, mouse |2 NLM Chemicals |
| 650 | _ | 7 | |a Carrier Proteins |2 NLM Chemicals |
| 650 | _ | 7 | |a Intracellular Signaling Peptides and Proteins |2 NLM Chemicals |
| 650 | _ | 7 | |a Membrane Proteins |2 NLM Chemicals |
| 650 | _ | 7 | |a Receptors, AMPA |2 NLM Chemicals |
| 650 | _ | 7 | |a Glutamic Acid |0 3KX376GY7L |2 NLM Chemicals |
| 650 | _ | 7 | |a cyclothiazide |0 P71U09G5BW |2 NLM Chemicals |
| 650 | _ | 2 | |a Animals |2 MeSH |
| 650 | _ | 2 | |a Benzothiadiazines: metabolism |2 MeSH |
| 650 | _ | 2 | |a Brain: embryology |2 MeSH |
| 650 | _ | 2 | |a Carrier Proteins: genetics |2 MeSH |
| 650 | _ | 2 | |a Carrier Proteins: metabolism |2 MeSH |
| 650 | _ | 2 | |a Gene Expression Regulation, Developmental |2 MeSH |
| 650 | _ | 2 | |a Glutamic Acid: metabolism |2 MeSH |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Intracellular Signaling Peptides and Proteins |2 MeSH |
| 650 | _ | 2 | |a Membrane Proteins: genetics |2 MeSH |
| 650 | _ | 2 | |a Membrane Proteins: metabolism |2 MeSH |
| 650 | _ | 2 | |a Mice |2 MeSH |
| 650 | _ | 2 | |a Protein Binding |2 MeSH |
| 650 | _ | 2 | |a Receptors, AMPA: agonists |2 MeSH |
| 650 | _ | 2 | |a Receptors, AMPA: metabolism |2 MeSH |
| 650 | _ | 2 | |a Sequence Analysis, DNA |2 MeSH |
| 700 | 1 | _ | |a Khodosevich, Konstantin |b 1 |
| 700 | 1 | _ | |a Sapir, Yechiam |b 2 |
| 700 | 1 | _ | |a Schulmann, Anton |b 3 |
| 700 | 1 | _ | |a Aslam, Muhammad |0 P:(DE-2719)2810579 |b 4 |u dzne |
| 700 | 1 | _ | |a Stern-Bach, Yael |b 5 |
| 700 | 1 | _ | |a Monyer, Hannah |b 6 |
| 700 | 1 | _ | |a Engelhardt, Jakob |0 P:(DE-2719)2810460 |b 7 |e Last author |u dzne |
| 773 | 1 | 8 | |a 10.7554/elife.09693 |b : eLife Sciences Publications, Ltd, 2015-12-01 |3 journal-article |2 Crossref |t eLife |v 4 |y 2015 |x 2050-084X |
| 773 | _ | _ | |a 10.7554/eLife.09693 |g Vol. 4, p. e09693 |0 PERI:(DE-600)2687154-3 |q 4 |t eLife |v 4 |y 2015 |x 2050-084X |
| 856 | 4 | _ | |y OpenAccess |u https://pub.dzne.de/record/138492/files/DZNE-2020-04814.pdf |
| 856 | 4 | _ | |y OpenAccess |x pdfa |u https://pub.dzne.de/record/138492/files/DZNE-2020-04814.pdf?subformat=pdfa |
| 856 | 7 | _ | |2 Pubmed Central |u http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733035 |
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