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000138903 041__ $$aEnglish
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000138903 1001_ $$0P:(DE-2719)2810704$$aKlopstock, Thomas$$b0$$eFirst author$$udzne
000138903 245__ $$aMitochondrial replacement approaches: challenges for clinical implementation.
000138903 260__ $$aLondon$$bBioMed Central$$c2016
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000138903 520__ $$aThe advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches.
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000138903 650_7 $$2NLM Chemicals$$aDNA, Mitochondrial
000138903 650_2 $$2MeSH$$aAnimals
000138903 650_2 $$2MeSH$$aDNA, Mitochondrial: genetics
000138903 650_2 $$2MeSH$$aFemale
000138903 650_2 $$2MeSH$$aFertilization in Vitro: ethics
000138903 650_2 $$2MeSH$$aGenes, Mitochondrial
000138903 650_2 $$2MeSH$$aHaplorhini
000138903 650_2 $$2MeSH$$aHumans
000138903 650_2 $$2MeSH$$aInheritance Patterns
000138903 650_2 $$2MeSH$$aMale
000138903 650_2 $$2MeSH$$aMice
000138903 650_2 $$2MeSH$$aMitochondria: genetics
000138903 650_2 $$2MeSH$$aMitochondria: transplantation
000138903 650_2 $$2MeSH$$aMitochondrial Diseases: genetics
000138903 650_2 $$2MeSH$$aMitochondrial Diseases: pathology
000138903 650_2 $$2MeSH$$aMitochondrial Diseases: prevention & control
000138903 650_2 $$2MeSH$$aMitochondrial Replacement Therapy: ethics
000138903 650_2 $$2MeSH$$aMitochondrial Replacement Therapy: methods
000138903 650_2 $$2MeSH$$aOocytes: metabolism
000138903 650_2 $$2MeSH$$aOocytes: pathology
000138903 650_2 $$2MeSH$$aSpermatozoa: cytology
000138903 650_2 $$2MeSH$$aSpermatozoa: metabolism
000138903 650_2 $$2MeSH$$aSpindle Apparatus: genetics
000138903 650_2 $$2MeSH$$aSpindle Apparatus: transplantation
000138903 7001_ $$aKlopstock, Barbara$$b1
000138903 7001_ $$aProkisch, Holger$$b2
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