Journal Article (Editorial)

DZNE-2020-05225

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Mitochondrial replacement approaches: challenges for clinical implementation.

Klopstock, T. (First author)DZNE* ; Klopstock, B. ; Prokisch, H.

2016
BioMed Central London

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Please use a persistent id in citations: doi:10.1186/s13073-016-0380-2

Abstract: The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches.

Keyword(s): Animals (MeSH) ; DNA, Mitochondrial: genetics (MeSH) ; Female (MeSH) ; Fertilization in Vitro: ethics (MeSH) ; Genes, Mitochondrial (MeSH) ; Haplorhini (MeSH) ; Humans (MeSH) ; Inheritance Patterns (MeSH) ; Male (MeSH) ; Mice (MeSH) ; Mitochondria: genetics (MeSH) ; Mitochondria: transplantation (MeSH) ; Mitochondrial Diseases: genetics (MeSH) ; Mitochondrial Diseases: pathology (MeSH) ; Mitochondrial Diseases: prevention & control (MeSH) ; Mitochondrial Replacement Therapy: ethics (MeSH) ; Mitochondrial Replacement Therapy: methods (MeSH) ; Oocytes: metabolism (MeSH) ; Oocytes: pathology (MeSH) ; Spermatozoa: cytology (MeSH) ; Spermatozoa: metabolism (MeSH) ; Spindle Apparatus: genetics (MeSH) ; Spindle Apparatus: transplantation (MeSH) ; DNA, Mitochondrial

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Contributing Institute(s):

1. Clinical Neurodegeneration (AG Levin)

Research Program(s):

1. 344 - Clinical and Health Care Research (POF3-344) (POF3-344)

Appears in the scientific report 2016

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Database coverage:
; ; ; ; BIOSIS Previews ; Clarivate Analytics Master Journal List ; DOAJ Seal ; Ebsco Academic Search ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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