Home > Publications Database > Mitochondrial replacement approaches: challenges for clinical implementation. > print

001     138903
005     20240605120502.0
024 7 _ |a 10.1186/s13073-016-0380-2
|2 doi
024 7 _ |a pmid:27887638
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024 7 _ |a pmc:PMC5124262
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024 7 _ |a altmetric:14124516
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037 _ _ |a DZNE-2020-05225
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Klopstock, Thomas
|0 P:(DE-2719)2810704
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|e First author
|u dzne
245 _ _ |a Mitochondrial replacement approaches: challenges for clinical implementation.
260 _ _ |a London
|c 2016
|b BioMed Central
264 _ 1 |3 online
|2 Crossref
|b Springer Science and Business Media LLC
|c 2016-11-25
264 _ 1 |3 print
|2 Crossref
|b Springer Science and Business Media LLC
|c 2016-12-01
336 7 _ |a article
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336 7 _ |a ARTICLE
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336 7 _ |a JOURNAL_ARTICLE
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336 7 _ |a Journal Article
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520 _ _ |a The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches.
536 _ _ |a 344 - Clinical and Health Care Research (POF3-344)
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588 _ _ |a Dataset connected to CrossRef, PubMed,
650 _ 7 |a DNA, Mitochondrial
|2 NLM Chemicals
650 _ 2 |a Animals
|2 MeSH
650 _ 2 |a DNA, Mitochondrial: genetics
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Fertilization in Vitro: ethics
|2 MeSH
650 _ 2 |a Genes, Mitochondrial
|2 MeSH
650 _ 2 |a Haplorhini
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Inheritance Patterns
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Mice
|2 MeSH
650 _ 2 |a Mitochondria: genetics
|2 MeSH
650 _ 2 |a Mitochondria: transplantation
|2 MeSH
650 _ 2 |a Mitochondrial Diseases: genetics
|2 MeSH
650 _ 2 |a Mitochondrial Diseases: pathology
|2 MeSH
650 _ 2 |a Mitochondrial Diseases: prevention & control
|2 MeSH
650 _ 2 |a Mitochondrial Replacement Therapy: ethics
|2 MeSH
650 _ 2 |a Mitochondrial Replacement Therapy: methods
|2 MeSH
650 _ 2 |a Oocytes: metabolism
|2 MeSH
650 _ 2 |a Oocytes: pathology
|2 MeSH
650 _ 2 |a Spermatozoa: cytology
|2 MeSH
650 _ 2 |a Spermatozoa: metabolism
|2 MeSH
650 _ 2 |a Spindle Apparatus: genetics
|2 MeSH
650 _ 2 |a Spindle Apparatus: transplantation
|2 MeSH
700 1 _ |a Klopstock, Barbara
|b 1
700 1 _ |a Prokisch, Holger
|b 2
773 1 8 |a 10.1186/s13073-016-0380-2
|b : Springer Science and Business Media LLC, 2016-11-25
|n 1
|p 126
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|t Genome Medicine
|v 8
|y 2016
|x 1756-994X
773 _ _ |a 10.1186/s13073-016-0380-2
|g Vol. 8, no. 1, p. 126
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|q 8:1<126
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|t Genome medicine
|v 8
|y 2016
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856 4 _ |y OpenAccess
|u https://pub.dzne.de/record/138903/files/DZNE-2020-05225.pdf
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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914 1 _ |y 2016
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999 C 5 |9 -- missing cx lookup --
|a 10.1093/humrep/des439
|2 Crossref
|o 10.1093/humrep/des439
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature18303
|2 Crossref
|o 10.1038/nature18303
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.cmet.2016.06.012
|2 Crossref
|o 10.1016/j.cmet.2016.06.012
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature11647
|2 Crossref
|o 10.1038/nature11647
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature14546
|2 Crossref
|o 10.1038/nature14546
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.tig.2016.04.006
|2 Crossref
|o 10.1016/j.tig.2016.04.006
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.fertnstert.2014.10.028
|2 Crossref
|o 10.1016/j.fertnstert.2014.10.028
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature.2016.19290
|2 Crossref
|o 10.1038/nature.2016.19290
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature.2016.20698
|2 Crossref
|o 10.1038/nature.2016.20698
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature.2016.20849
|2 Crossref
|o 10.1038/nature.2016.20849

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