Home > Publications Database > Hippocampal and prefrontal processing of network topology to simulate the future. > print

001     139118
005     20240515120217.0
024 7 _ |a 10.1038/ncomms14652
|2 doi
024 7 _ |a pmid:28323817
|2 pmid
024 7 _ |a pmc:PMC5364395
|2 pmc
024 7 _ |a altmetric:17861337
|2 altmetric
037 _ _ |a DZNE-2020-05440
041 _ _ |a English
082 _ _ |a 500
100 1 _ |a Javadi, Amir-Homayoun
|0 P:(DE-HGF)0
|b 0
245 _ _ |a Hippocampal and prefrontal processing of network topology to simulate the future.
260 _ _ |a [London]
|c 2017
|b Nature Publishing Group UK
264 _ 1 |3 online
|2 Crossref
|b Springer Science and Business Media LLC
|c 2017-03-21
264 _ 1 |3 print
|2 Crossref
|b Springer Science and Business Media LLC
|c 2017-04-01
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1715693439_2120
|2 PUB:(DE-HGF)
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
520 _ _ |a Topological networks lie at the heart of our cities and social milieu. However, it remains unclear how and when the brain processes topological structures to guide future behaviour during everyday life. Using fMRI in humans and a simulation of London (UK), here we show that, specifically when new streets are entered during navigation of the city, right posterior hippocampal activity indexes the change in the number of local topological connections available for future travel and right anterior hippocampal activity reflects global properties of the street entered. When forced detours require re-planning of the route to the goal, bilateral inferior lateral prefrontal activity scales with the planning demands of a breadth-first search of future paths. These results help shape models of how hippocampal and prefrontal regions support navigation, planning and future simulation.
536 _ _ |a 344 - Clinical and Health Care Research (POF3-344)
|0 G:(DE-HGF)POF3-344
|c POF3-344
|f POF III
|x 0
542 _ _ |i 2017-03-21
|2 Crossref
|u https://creativecommons.org/licenses/by/4.0
588 _ _ |a Dataset connected to CrossRef, PubMed,
650 _ 2 |a Adult
|2 MeSH
650 _ 2 |a Brain: diagnostic imaging
|2 MeSH
650 _ 2 |a Brain: physiology
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Functional Neuroimaging
|2 MeSH
650 _ 2 |a Hippocampus: diagnostic imaging
|2 MeSH
650 _ 2 |a Hippocampus: physiology
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a London
|2 MeSH
650 _ 2 |a Magnetic Resonance Imaging
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Prefrontal Cortex: diagnostic imaging
|2 MeSH
650 _ 2 |a Prefrontal Cortex: physiology
|2 MeSH
650 _ 2 |a Spatial Behavior: physiology
|2 MeSH
650 _ 2 |a Spatial Navigation: physiology
|2 MeSH
650 _ 2 |a Spatial Processing: physiology
|2 MeSH
650 _ 2 |a Young Adult
|2 MeSH
700 1 _ |a Emo, Beatrix
|0 P:(DE-HGF)0
|b 1
700 1 _ |a Howard, Lorelei R
|0 P:(DE-2719)2810709
|b 2
|u dzne
700 1 _ |a Zisch, Fiona E
|0 P:(DE-HGF)0
|b 3
700 1 _ |a Yu, Yichao
|0 P:(DE-HGF)0
|b 4
700 1 _ |a Knight, Rebecca
|0 P:(DE-HGF)0
|b 5
700 1 _ |a Pinelo Silva, Joao
|0 P:(DE-HGF)0
|b 6
700 1 _ |a Spiers, Hugo J
|0 P:(DE-HGF)0
|b 7
|e Corresponding author
773 1 8 |a 10.1038/ncomms14652
|b : Springer Science and Business Media LLC, 2017-03-21
|n 1
|p 14652
|3 journal-article
|2 Crossref
|t Nature Communications
|v 8
|y 2017
|x 2041-1723
773 _ _ |a 10.1038/ncomms14652
|g Vol. 8, no. 1, p. 14652
|0 PERI:(DE-600)2553671-0
|n 1
|q 8:1<14652
|p 14652
|t Nature Communications
|v 8
|y 2017
|x 2041-1723
856 4 _ |y OpenAccess
|u https://pub.dzne.de/record/139118/files/DZNE-2020-05440.pdf
856 4 _ |y OpenAccess
|x pdfa
|u https://pub.dzne.de/record/139118/files/DZNE-2020-05440.pdf?subformat=pdfa
856 7 _ |2 Pubmed Central
|u http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364395
909 C O |o oai:pub.dzne.de:139118
|p openaire
|p open_access
|p VDB
|p driver
|p dnbdelivery
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 2
|6 P:(DE-2719)2810709
913 1 _ |a DE-HGF
|b Gesundheit
|l Erkrankungen des Nervensystems
|1 G:(DE-HGF)POF3-340
|0 G:(DE-HGF)POF3-344
|3 G:(DE-HGF)POF3
|2 G:(DE-HGF)POF3-300
|4 G:(DE-HGF)POF
|v Clinical and Health Care Research
|x 0
914 1 _ |y 2017
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
|d 2022-11-11
915 _ _ |a Creative Commons Attribution CC BY (No Version)
|0 LIC:(DE-HGF)CCBYNV
|2 V:(DE-HGF)
|b DOAJ
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1050
|2 StatID
|b BIOSIS Previews
|d 2022-11-11
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1040
|2 StatID
|b Zoological Record
|d 2022-11-11
915 _ _ |a IF >= 15
|0 StatID:(DE-HGF)9915
|2 StatID
|b NAT COMMUN : 2021
|d 2022-11-11
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b NAT COMMUN : 2021
|d 2022-11-11
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0501
|2 StatID
|b DOAJ Seal
|d 2021-10-13T14:44:21Z
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0500
|2 StatID
|b DOAJ
|d 2021-10-13T14:44:21Z
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1030
|2 StatID
|b Current Contents - Life Sciences
|d 2022-11-11
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
|d 2022-11-11
915 _ _ |a OpenAccess
|0 StatID:(DE-HGF)0510
|2 StatID
915 _ _ |a Peer Review
|0 StatID:(DE-HGF)0030
|2 StatID
|b DOAJ : Peer review
|d 2021-10-13T14:44:21Z
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1060
|2 StatID
|b Current Contents - Agriculture, Biology and Environmental Sciences
|d 2022-11-11
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
|d 2022-11-11
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1150
|2 StatID
|b Current Contents - Physical, Chemical and Earth Sciences
|d 2022-11-11
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Clarivate Analytics Master Journal List
|d 2022-11-11
920 1 _ |0 I:(DE-2719)1310002
|k AG Wolbers
|l Aging, Cognition and Technology
|x 0
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a UNRESTRICTED
980 _ _ |a I:(DE-2719)1310002
980 1 _ |a FullTexts
999 C 5 |9 -- missing cx lookup --
|a 10.1098/rstb.2008.0296
|2 Crossref
|o 10.1098/rstb.2008.0296
999 C 5 |9 -- missing cx lookup --
|a 10.1111/j.1460-9568.2012.08015.x
|2 Crossref
|o 10.1111/j.1460-9568.2012.08015.x
999 C 5 |9 -- missing cx lookup --
|a 10.1037/0033-295X.114.2.340
|2 Crossref
|o 10.1037/0033-295X.114.2.340
999 C 5 |9 -- missing cx lookup --
|a 10.7554/eLife.06063
|2 Crossref
|o 10.7554/eLife.06063
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.neuron.2012.11.001
|2 Crossref
|o 10.1016/j.neuron.2012.11.001
999 C 5 |9 -- missing cx lookup --
|a 10.1093/cercor/bht198
|2 Crossref
|o 10.1093/cercor/bht198
999 C 5 |9 -- missing cx lookup --
|a 10.7554/eLife.03476
|2 Crossref
|o 10.7554/eLife.03476
999 C 5 |9 -- missing cx lookup --
|a 10.1523/JNEUROSCI.3414-13.2014
|2 Crossref
|o 10.1523/JNEUROSCI.3414-13.2014
999 C 5 |9 -- missing cx lookup --
|a 10.1093/brain/114.2.727
|2 Crossref
|o 10.1093/brain/114.2.727
999 C 5 |9 -- missing cx lookup --
|a 10.3389/fnhum.2015.00125
|2 Crossref
|o 10.3389/fnhum.2015.00125
999 C 5 |9 -- missing cx lookup --
|a 10.1371/journal.pcbi.1002410
|2 Crossref
|o 10.1371/journal.pcbi.1002410
999 C 5 |9 -- missing cx lookup --
|a 10.1073/pnas.1414219112
|2 Crossref
|o 10.1073/pnas.1414219112
999 C 5 |y 2005
|2 Crossref
|o S Russell 2005
999 C 5 |2 Crossref
|o
999 C 5 |9 -- missing cx lookup --
|a 10.1007/BF02289527
|2 Crossref
|o 10.1007/BF02289527
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.cub.2014.05.001
|2 Crossref
|o 10.1016/j.cub.2014.05.001
999 C 5 |9 -- missing cx lookup --
|a 10.3390/bs4030167
|2 Crossref
|o 10.3390/bs4030167
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.cobeha.2014.08.005
|2 Crossref
|o 10.1016/j.cobeha.2014.08.005
999 C 5 |9 -- missing cx lookup --
|a 10.1523/JNEUROSCI.3761-07.2007
|2 Crossref
|o 10.1523/JNEUROSCI.3761-07.2007
999 C 5 |9 -- missing cx lookup --
|a 10.1038/nature12112
|2 Crossref
|o 10.1038/nature12112
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.conb.2008.01.003
|2 Crossref
|o 10.1016/j.conb.2008.01.003
999 C 5 |9 -- missing cx lookup --
|a 10.1002/hipo.20233
|2 Crossref
|o 10.1002/hipo.20233
999 C 5 |9 -- missing cx lookup --
|a 10.1016/S0028-3932(97)00161-9
|2 Crossref
|o 10.1016/S0028-3932(97)00161-9
999 C 5 |9 -- missing cx lookup --
|a 10.1073/pnas.0801489105
|2 Crossref
|o 10.1073/pnas.0801489105
999 C 5 |9 -- missing cx lookup --
|a 10.1523/JNEUROSCI.0350-13.2013
|2 Crossref
|o 10.1523/JNEUROSCI.0350-13.2013
999 C 5 |9 -- missing cx lookup --
|a 10.1093/brain/124.12.2476
|2 Crossref
|o 10.1093/brain/124.12.2476
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.neuron.2015.06.011
|2 Crossref
|o 10.1016/j.neuron.2015.06.011
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.tics.2013.03.005
|2 Crossref
|o 10.1016/j.tics.2013.03.005
999 C 5 |9 -- missing cx lookup --
|a 10.1162/jocn_a_00313
|2 Crossref
|o 10.1162/jocn_a_00313
999 C 5 |9 -- missing cx lookup --
|a 10.1111/ejn.13218
|2 Crossref
|o 10.1111/ejn.13218
999 C 5 |9 -- missing cx lookup --
|a 10.1002/hipo.22523
|2 Crossref
|o 10.1002/hipo.22523
999 C 5 |9 -- missing cx lookup --
|a 10.1177/0013916502238867
|2 Crossref
|o 10.1177/0013916502238867
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.neunet.2004.12.004
|2 Crossref
|o 10.1016/j.neunet.2004.12.004
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.neunet.2005.11.002
|2 Crossref
|o 10.1016/j.neunet.2005.11.002
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.neuron.2016.03.037
|2 Crossref
|o 10.1016/j.neuron.2016.03.037
999 C 5 |9 -- missing cx lookup --
|a 10.3389/fnbeh.2015.00292
|2 Crossref
|o 10.3389/fnbeh.2015.00292
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.neuroimage.2006.01.037
|2 Crossref
|o 10.1016/j.neuroimage.2006.01.037
999 C 5 |9 -- missing cx lookup --
|a 10.1016/j.intell.2005.09.005
|2 Crossref
|o 10.1016/j.intell.2005.09.005
999 C 5 |9 -- missing cx lookup --
|a 10.4324/9780203101728
|2 Crossref
|o 10.4324/9780203101728
999 C 5 |9 -- missing cx lookup --
|a 10.2307/3033543
|2 Crossref
|o 10.2307/3033543
999 C 5 |9 -- missing cx lookup --
|a 10.1068/b200029
|2 Crossref
|o 10.1068/b200029
999 C 5 |9 -- missing cx lookup --
|a 10.1007/11556114_30
|2 Crossref
|o 10.1007/11556114_30
999 C 5 |9 -- missing cx lookup --
|a 10.1177/0013916502238864
|2 Crossref
|o 10.1177/0013916502238864
999 C 5 |9 -- missing cx lookup --
|a 10.1177/0013916590225001
|2 Crossref
|o 10.1177/0013916590225001
999 C 5 |9 -- missing cx lookup --
|a 10.1006/jevp.2001.0225
|2 Crossref
|o 10.1006/jevp.2001.0225
999 C 5 |9 -- missing cx lookup --
|a 10.1002/(SICI)1097-0193(1997)5:4<243::AID-HBM7>3.0.CO;2-3
|2 Crossref
|o 10.1002/(SICI)1097-0193(1997)5:4<243::AID-HBM7>3.0.CO;2-3
999 C 5 |9 -- missing cx lookup --
|a 10.1371/journal.pone.0126255
|2 Crossref
|o 10.1371/journal.pone.0126255
999 C 5 |9 -- missing cx lookup --
|a 10.1002/hipo.20298
|2 Crossref
|o 10.1002/hipo.20298
999 C 5 |9 -- missing cx lookup --
|a 10.1126/science.280.5365.921
|2 Crossref
|o 10.1126/science.280.5365.921
999 C 5 |9 -- missing cx lookup --
|a 10.1523/JNEUROSCI.17-18-07103.1997
|2 Crossref
|o 10.1523/JNEUROSCI.17-18-07103.1997
999 C 5 |9 -- missing cx lookup --
|a 10.1523/JNEUROSCI.6055-10.2011
|2 Crossref
|o 10.1523/JNEUROSCI.6055-10.2011
999 C 5 |y 2002
|2 Crossref
|o M Brett 2002
999 C 5 |9 -- missing cx lookup --
|a 10.1016/S1053-8119(03)00169-1
|2 Crossref
|o 10.1016/S1053-8119(03)00169-1

LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21