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000139697 0247_ $$2doi$$a10.2174/1567205014666170908095707
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000139697 0247_ $$2ISSN$$a1567-2050
000139697 0247_ $$2ISSN$$a1875-5828
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000139697 037__ $$aDZNE-2020-06019
000139697 041__ $$aEnglish
000139697 082__ $$a610
000139697 1001_ $$0P:(DE-2719)2810514$$aEichler, Tilly$$b0$$eFirst author$$udzne
000139697 245__ $$aPatient Variables Associated with the Assignment of a Formal Dementia Diagnosis to Positively Screened Primary Care Patients.
000139697 260__ $$aHilversum$$bBentham Science Publ. Ltd.$$c2018
000139697 264_1 $$2Crossref$$3print$$bBentham Science Publishers Ltd.$$c2017-12-21
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000139697 520__ $$aMain objective was to analyze the associations of patient variables (depression, quality of life, anti-dementia drug treatment, knowledge about dementia) with the assignment of a formal diagnosis of dementia to community-dwelling primary care patients who have screened positive for dementia.DelpHi-MV (Dementia: life- and person-centered help in Mecklenburg-Western Pomerania) is a general practitioner based randomized controlled intervention trial. Present analyses are based on cross-sectional data of 319 positively screened patients (age 70+, living at home) who had not been formally diagnosed with dementia before the screening. The medical diagnoses (ICD-10) were retrieved from the patient's medical records. Depression (Geriatric Depression Scale; GDS), quality of life in Alzheimer's disease (Qol-AD), knowledge about dementia, and anti-dementia drug treatment were assessed after the screening test at the baseline examination.At the baseline examination, 171 out of 319 patients (54%) had been formally diagnosed with dementia after they have screened positive. Univariate comparisons showed no statistically significant differences between diagnosed and undiagnosed patients regarding depression (GDS≥6: 11% vs. 15%; p=0.396), quality of life (mean (SD): 2.8 (0.3) vs. 2.8 (0.4); p=0.833), and the knowledge about dementia (75% vs. 75%; p>0.999). Patients who had received a formal diagnosis were more often treated with anti-dementia drugs (20% vs. 11%; p=0.040). Multivariate analyses controlled for confounding variables confirmed these findings.Present findings do not support concerns that the assignment of a formal dementia diagnosis after screening is associated with potential harms. If confirmed in a prospective study, our data would suggest that patients may benefit from being formally diagnosed regarding anti-dementia drug treatment.
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000139697 650_7 $$2NLM Chemicals$$aNootropic Agents
000139697 650_2 $$2MeSH$$aAged
000139697 650_2 $$2MeSH$$aAged, 80 and over
000139697 650_2 $$2MeSH$$aCross-Sectional Studies
000139697 650_2 $$2MeSH$$aDementia: diagnosis
000139697 650_2 $$2MeSH$$aDementia: drug therapy
000139697 650_2 $$2MeSH$$aDementia: epidemiology
000139697 650_2 $$2MeSH$$aDementia: psychology
000139697 650_2 $$2MeSH$$aDepression: epidemiology
000139697 650_2 $$2MeSH$$aFemale
000139697 650_2 $$2MeSH$$aHealth Knowledge, Attitudes, Practice
000139697 650_2 $$2MeSH$$aHumans
000139697 650_2 $$2MeSH$$aMale
000139697 650_2 $$2MeSH$$aNootropic Agents: therapeutic use
000139697 650_2 $$2MeSH$$aPrimary Health Care
000139697 650_2 $$2MeSH$$aQuality of Life
000139697 7001_ $$0P:(DE-2719)2290613$$aThyrian, Jochen Rene$$b1$$eCorresponding author$$udzne
000139697 7001_ $$0P:(DE-2719)2810814$$aHertel, Johannes$$b2$$udzne
000139697 7001_ $$0P:(DE-2719)2811043$$aRichter, Steffen$$b3$$udzne
000139697 7001_ $$0P:(DE-2719)2810763$$aMichalowsky, Bernhard$$b4$$udzne
000139697 7001_ $$0P:(DE-2719)2810631$$aWucherer, Diana$$b5$$udzne
000139697 7001_ $$0P:(DE-2719)2813139$$aDreier, Adina$$b6$$udzne
000139697 7001_ $$0P:(DE-2719)2810394$$aKilimann, Ingo$$b7$$udzne
000139697 7001_ $$0P:(DE-2719)2000026$$aTeipel, Stefan$$b8$$udzne
000139697 7001_ $$0P:(DE-2719)2000040$$aHoffmann, Wolfgang$$b9$$eLast author$$udzne
000139697 77318 $$2Crossref$$3journal-article$$a10.2174/1567205014666170908095707$$b : Bentham Science Publishers Ltd., 2017-12-21$$n1$$tCurrent Alzheimer Research$$v15$$x1567-2050$$y2017
000139697 773__ $$0PERI:(DE-600)2155964-8$$a10.2174/1567205014666170908095707$$gVol. 15, no. 1$$n1$$p44-50$$q15:1$$tCurrent Alzheimer research$$v15$$x1567-2050$$y2017
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