Journal Article DZNE-2020-06019

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Patient Variables Associated with the Assignment of a Formal Dementia Diagnosis to Positively Screened Primary Care Patients.

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2018
Bentham Science Publ. Ltd. Hilversum

Current Alzheimer research 15(1), 44-50 () [10.2174/1567205014666170908095707]

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Abstract: Main objective was to analyze the associations of patient variables (depression, quality of life, anti-dementia drug treatment, knowledge about dementia) with the assignment of a formal diagnosis of dementia to community-dwelling primary care patients who have screened positive for dementia.DelpHi-MV (Dementia: life- and person-centered help in Mecklenburg-Western Pomerania) is a general practitioner based randomized controlled intervention trial. Present analyses are based on cross-sectional data of 319 positively screened patients (age 70+, living at home) who had not been formally diagnosed with dementia before the screening. The medical diagnoses (ICD-10) were retrieved from the patient's medical records. Depression (Geriatric Depression Scale; GDS), quality of life in Alzheimer's disease (Qol-AD), knowledge about dementia, and anti-dementia drug treatment were assessed after the screening test at the baseline examination.At the baseline examination, 171 out of 319 patients (54%) had been formally diagnosed with dementia after they have screened positive. Univariate comparisons showed no statistically significant differences between diagnosed and undiagnosed patients regarding depression (GDS≥6: 11% vs. 15%; p=0.396), quality of life (mean (SD): 2.8 (0.3) vs. 2.8 (0.4); p=0.833), and the knowledge about dementia (75% vs. 75%; p>0.999). Patients who had received a formal diagnosis were more often treated with anti-dementia drugs (20% vs. 11%; p=0.040). Multivariate analyses controlled for confounding variables confirmed these findings.Present findings do not support concerns that the assignment of a formal dementia diagnosis after screening is associated with potential harms. If confirmed in a prospective study, our data would suggest that patients may benefit from being formally diagnosed regarding anti-dementia drug treatment.

Keyword(s): Aged (MeSH) ; Aged, 80 and over (MeSH) ; Cross-Sectional Studies (MeSH) ; Dementia: diagnosis (MeSH) ; Dementia: drug therapy (MeSH) ; Dementia: epidemiology (MeSH) ; Dementia: psychology (MeSH) ; Depression: epidemiology (MeSH) ; Female (MeSH) ; Health Knowledge, Attitudes, Practice (MeSH) ; Humans (MeSH) ; Male (MeSH) ; Nootropic Agents: therapeutic use (MeSH) ; Primary Health Care (MeSH) ; Quality of Life (MeSH) ; Nootropic Agents

Classification:

Contributing Institute(s):
  1. Interventional Health Care Research (IHCR) (AG Thyrian)
  2. Biomarkers of dementia in the general population (AG Grabe)
  3. Magdeburg Pre 2020 (Magdeburg Pre 2020)
  4. Translational Health Care Research (Translational Health Care Research)
  5. Clinical Dementia Research Rostock /Greifswald (Clinical Dementia Research Rostock /Greifswald ; AG Teipel)
Research Program(s):
  1. 344 - Clinical and Health Care Research (POF3-344) (POF3-344)

Appears in the scientific report 2018
Database coverage:
Medline ; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; Clarivate Analytics Master Journal List ; IF < 5 ; JCR ; SCOPUS ; Web of Science Core Collection
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The record appears in these collections:
Institute Collections > MD DZNE > MD DZNE-Magdeburg common
Document types > Articles > Journal Article
Institute Collections > ROS DZNE > ROS DZNE-AG Hoffmann
Institute Collections > ROS DZNE > ROS DZNE-AG Thyrian
Institute Collections > ROS DZNE > ROS DZNE-AG Teipel
Institute Collections > ROS DZNE > ROS DZNE-AG Grabe
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 Record created 2020-02-18, last modified 2024-03-21



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