001     139697
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024 7 _ |a 10.2174/1567205014666170908095707
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024 7 _ |a 1567-2050
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024 7 _ |a 1875-5828
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037 _ _ |a DZNE-2020-06019
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Eichler, Tilly
|0 P:(DE-2719)2810514
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245 _ _ |a Patient Variables Associated with the Assignment of a Formal Dementia Diagnosis to Positively Screened Primary Care Patients.
260 _ _ |a Hilversum
|c 2018
|b Bentham Science Publ. Ltd.
264 _ 1 |3 print
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|c 2017-12-21
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520 _ _ |a Main objective was to analyze the associations of patient variables (depression, quality of life, anti-dementia drug treatment, knowledge about dementia) with the assignment of a formal diagnosis of dementia to community-dwelling primary care patients who have screened positive for dementia.DelpHi-MV (Dementia: life- and person-centered help in Mecklenburg-Western Pomerania) is a general practitioner based randomized controlled intervention trial. Present analyses are based on cross-sectional data of 319 positively screened patients (age 70+, living at home) who had not been formally diagnosed with dementia before the screening. The medical diagnoses (ICD-10) were retrieved from the patient's medical records. Depression (Geriatric Depression Scale; GDS), quality of life in Alzheimer's disease (Qol-AD), knowledge about dementia, and anti-dementia drug treatment were assessed after the screening test at the baseline examination.At the baseline examination, 171 out of 319 patients (54%) had been formally diagnosed with dementia after they have screened positive. Univariate comparisons showed no statistically significant differences between diagnosed and undiagnosed patients regarding depression (GDS≥6: 11% vs. 15%; p=0.396), quality of life (mean (SD): 2.8 (0.3) vs. 2.8 (0.4); p=0.833), and the knowledge about dementia (75% vs. 75%; p>0.999). Patients who had received a formal diagnosis were more often treated with anti-dementia drugs (20% vs. 11%; p=0.040). Multivariate analyses controlled for confounding variables confirmed these findings.Present findings do not support concerns that the assignment of a formal dementia diagnosis after screening is associated with potential harms. If confirmed in a prospective study, our data would suggest that patients may benefit from being formally diagnosed regarding anti-dementia drug treatment.
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650 _ 7 |a Nootropic Agents
|2 NLM Chemicals
650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Aged, 80 and over
|2 MeSH
650 _ 2 |a Cross-Sectional Studies
|2 MeSH
650 _ 2 |a Dementia: diagnosis
|2 MeSH
650 _ 2 |a Dementia: drug therapy
|2 MeSH
650 _ 2 |a Dementia: epidemiology
|2 MeSH
650 _ 2 |a Dementia: psychology
|2 MeSH
650 _ 2 |a Depression: epidemiology
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Health Knowledge, Attitudes, Practice
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Nootropic Agents: therapeutic use
|2 MeSH
650 _ 2 |a Primary Health Care
|2 MeSH
650 _ 2 |a Quality of Life
|2 MeSH
700 1 _ |a Thyrian, Jochen Rene
|0 P:(DE-2719)2290613
|b 1
|e Corresponding author
|u dzne
700 1 _ |a Hertel, Johannes
|0 P:(DE-2719)2810814
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700 1 _ |a Richter, Steffen
|0 P:(DE-2719)2811043
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700 1 _ |a Michalowsky, Bernhard
|0 P:(DE-2719)2810763
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700 1 _ |a Wucherer, Diana
|0 P:(DE-2719)2810631
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700 1 _ |a Dreier, Adina
|0 P:(DE-2719)2813139
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700 1 _ |a Kilimann, Ingo
|0 P:(DE-2719)2810394
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700 1 _ |a Teipel, Stefan
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700 1 _ |a Hoffmann, Wolfgang
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773 1 8 |a 10.2174/1567205014666170908095707
|b : Bentham Science Publishers Ltd., 2017-12-21
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|t Current Alzheimer Research
|v 15
|y 2017
|x 1567-2050
773 _ _ |a 10.2174/1567205014666170908095707
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