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@ARTICLE{Schroeter:139758,
      author       = {Schroeter, Matthias L and Pawelke, Sarah and Bisenius,
                      Sandrine and Kynast, Jana and Schuemberg, Katharina and
                      Polyakova, Maryna and Anderl-Straub, Sarah and Danek, Adrian
                      and Fassbender, Klaus and Jahn, Holger and Jessen, Frank and
                      Kornhuber, Johannes and Lauer, Martin and Prudlo, Johannes
                      and Schneider, Anja and Uttner, Ingo and Thöne-Otto,
                      Angelika and Otto, Markus and Diehl-Schmid, Janine},
      title        = {{A} {M}odified {R}eading the {M}ind in the {E}yes {T}est
                      {P}redicts {B}ehavioral {V}ariant {F}rontotemporal
                      {D}ementia {B}etter {T}han {E}xecutive {F}unction {T}ests.},
      journal      = {Frontiers in aging neuroscience},
      volume       = {10},
      issn         = {1663-4365},
      address      = {Lausanne},
      publisher    = {Frontiers Research Foundation},
      reportid     = {DZNE-2020-06080},
      pages        = {11},
      year         = {2018},
      abstract     = {Behavioral variant frontotemporal dementia (bvFTD) is
                      characterized by deep alterations in behavior and
                      personality. Although revised diagnostic criteria agree for
                      executive dysfunction as most characteristic, impairments in
                      social cognition are also suggested. The study aimed at
                      identifying those neuropsychological and behavioral
                      parameters best discriminating between bvFTD and healthy
                      controls. Eighty six patients were diagnosed with possible
                      or probable bvFTD according to Rascovsky et al. (2011) and
                      compared with 43 healthy age-matched controls.
                      Neuropsychological performance was assessed with a modified
                      Reading the Mind in the Eyes Test (RMET), Stroop task, Trail
                      Making Test (TMT), Hamasch-Five-Point Test (H5PT), and
                      semantic and phonemic verbal fluency tasks. Behavior was
                      assessed with the Apathy Evaluation Scale, Frontal Systems
                      Behavioral Scale, and Bayer Activities of Daily Living
                      Scale. Each test's discriminatory power was investigated by
                      Receiver Operating Characteristic curves calculating the
                      area under the curve (AUC). bvFTD patients performed
                      significantly worse than healthy controls in all
                      neuropsychological tests. Discriminatory power (AUC) was
                      highest in behavioral questionnaires, high in verbal fluency
                      tasks and the RMET, and lower in executive function tests
                      such as the Stroop task, TMT and H5PT. As fluency tasks
                      depend on several cognitive functions, not only executive
                      functions, results suggest that the RMET discriminated
                      better between bvFTD and control subjects than other
                      executive tests. Social cognition should be incorporated
                      into diagnostic criteria for bvFTD in the future, such as in
                      the International Classification of Diseases (ICD)-11, as
                      already suggested in the Diagnostic and Statistical Manual
                      for Mental Disorders (DSM)-5.},
      cin          = {AG Jessen / Clinical Dementia Research Bonn},
      ddc          = {610},
      cid          = {I:(DE-2719)1011102 / I:(DE-2719)1011305},
      pnm          = {344 - Clinical and Health Care Research (POF3-344)},
      pid          = {G:(DE-HGF)POF3-344},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29441012},
      pmc          = {pmc:PMC5797534},
      doi          = {10.3389/fnagi.2018.00011},
      url          = {https://pub.dzne.de/record/139758},
}