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| 024 | 7 | _ | |a 10.1016/j.neurol.2018.07.001 |2 doi |
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| 024 | 7 | _ | |a 0035-3787 |2 ISSN |
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| 037 | _ | _ | |a DZNE-2020-06606 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Höglinger, G. U. |0 P:(DE-2719)2811373 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a New classification of tauopathies. |
| 260 | _ | _ | |a Issy-les-Moulineaux |c 2018 |b Elsevier Masson |
| 264 | _ | 1 | |3 print |2 Crossref |b Elsevier BV |c 2018-11-01 |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a Tauopathies are a group of neurodegenerative diseases characterized by pathological intracellular deposits of the protein tau. Isoform composition, morphology and anatomical distribution of cellular tau-immunoreactivities are defining distinct tauopathies as molecular pathological disease entities. The clinical spectrum of tauopathies includes syndromes with primary motor symptoms and with primary cognitive dysfunction. The traditional syndrome-based classification is currently being complemented by a molecular-pathological classification. While the syndrome-based classification is helpful to select symptomatic therapies, and to generate clinical working hypotheses about underlying etiologies, the molecular-pathological classification is most important for the development and application of molecularly tailored disease-modifying therapies. |
| 536 | _ | _ | |a 344 - Clinical and Health Care Research (POF3-344) |0 G:(DE-HGF)POF3-344 |c POF3-344 |f POF III |x 0 |
| 542 | _ | _ | |i 2018-11-01 |2 Crossref |u https://www.elsevier.com/tdm/userlicense/1.0/ |
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| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Neurodegenerative Diseases: classification |2 MeSH |
| 650 | _ | 2 | |a Neurodegenerative Diseases: genetics |2 MeSH |
| 650 | _ | 2 | |a Supranuclear Palsy, Progressive: classification |2 MeSH |
| 650 | _ | 2 | |a Supranuclear Palsy, Progressive: genetics |2 MeSH |
| 650 | _ | 2 | |a Supranuclear Palsy, Progressive: physiopathology |2 MeSH |
| 650 | _ | 2 | |a Tauopathies: classification |2 MeSH |
| 650 | _ | 2 | |a Tauopathies: genetics |2 MeSH |
| 650 | _ | 2 | |a Tauopathies: physiopathology |2 MeSH |
| 700 | 1 | _ | |a Respondek, G. |0 P:(DE-2719)2811600 |b 1 |u dzne |
| 700 | 1 | _ | |a Kovacs, G. G. |b 2 |
| 773 | 1 | 8 | |a 10.1016/j.neurol.2018.07.001 |b : Elsevier BV, 2018-11-01 |n 9 |p 664-668 |3 journal-article |2 Crossref |t Revue Neurologique |v 174 |y 2018 |x 0035-3787 |
| 773 | _ | _ | |a 10.1016/j.neurol.2018.07.001 |g Vol. 174, no. 9, p. 664 - 668 |0 PERI:(DE-600)2036356-4 |n 9 |q 174:9<664 - 668 |p 664-668 |t Revue neurologique |v 174 |y 2018 |x 0035-3787 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/140284/files/DZNE-2020-06606_Restricted.pdf |
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