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@ARTICLE{Maetzler:140981,
author = {Maetzler, Walter and Rattay, Tim W and Hobert, Markus A and
Synofzik, Matthis and Bader, Angela and Berg, Daniela and
Schaeffer, Eva and Rommel, Natalie and Devos, David and
Bloem, Bastiaan R and Bender, Benjamin},
title = {{F}reezing of {S}wallowing.},
journal = {Movement disorders clinical practice},
volume = {3},
number = {5},
issn = {2330-1619},
address = {New York, NY},
publisher = {Wiley},
reportid = {DZNE-2020-07303},
pages = {490-493},
year = {2016},
abstract = {Swallowing deficits and freezing phenomena represent severe
parkinsonian features. Freezing as a symptom occurring
during swallowing has not been reported on yet.We report on
3 patients with probable PSP-parkinsonism (PSP-P) who
manifested freezing of swallowing (FOS).All 3 patients
experienced severe weight loss in recent months. At
examination, 1 patient had freezing of gait. Video
fluoroscopy showed nonfunctional trembling movements of the
tongue and palate during chewing and volitional swallowing,
with a 6- to 8-Hz frequency that is typical for freezing
episodes during walking and finger tapping. These freezing
episodes were accompanied by impaired oral bolus
transportation. The pharyngeal phase was not relevantly
affected.FOS represents a novel disease feature of PSP-P.
The feature may have fundamental, but potentially treatable,
consequences for patients' health and quality of life and
may be considered in patients with degenerative parkinsonism
who experience severe and unexplained weight loss.},
cin = {AG Maetzler / AG Gasser / Ext UKT / AG Berg / Tübingen
common},
ddc = {610},
cid = {I:(DE-2719)5000024 / I:(DE-2719)1210000 /
I:(DE-2719)5000058 / I:(DE-2719)5000055 /
I:(DE-2719)6000018},
pnm = {344 - Clinical and Health Care Research (POF3-344) / 345 -
Population Studies and Genetics (POF3-345)},
pid = {G:(DE-HGF)POF3-344 / G:(DE-HGF)POF3-345},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30868092},
pmc = {pmc:PMC6400494},
doi = {10.1002/mdc3.12314},
url = {https://pub.dzne.de/record/140981},
}