Journal Article DZNE-2020-07303

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Freezing of Swallowing.

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2016
Wiley New York, NY

Movement disorders clinical practice 3(5), 490-493 () [10.1002/mdc3.12314]

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Abstract: Swallowing deficits and freezing phenomena represent severe parkinsonian features. Freezing as a symptom occurring during swallowing has not been reported on yet.We report on 3 patients with probable PSP-parkinsonism (PSP-P) who manifested freezing of swallowing (FOS).All 3 patients experienced severe weight loss in recent months. At examination, 1 patient had freezing of gait. Video fluoroscopy showed nonfunctional trembling movements of the tongue and palate during chewing and volitional swallowing, with a 6- to 8-Hz frequency that is typical for freezing episodes during walking and finger tapping. These freezing episodes were accompanied by impaired oral bolus transportation. The pharyngeal phase was not relevantly affected.FOS represents a novel disease feature of PSP-P. The feature may have fundamental, but potentially treatable, consequences for patients' health and quality of life and may be considered in patients with degenerative parkinsonism who experience severe and unexplained weight loss.

Classification:

Contributing Institute(s):
  1. Functional Neurogeriatrics (AG Maetzler)
  2. Parkinson Genetics (AG Gasser)
  3. Ext Universitätsklinikum Tübingen (Ext UKT)
  4. Parkinson's Disease Genetics (AG Berg)
  5. Tübingen common (Tübingen common)
Research Program(s):
  1. 344 - Clinical and Health Care Research (POF3-344) (POF3-344)
  2. 345 - Population Studies and Genetics (POF3-345) (POF3-345)

Appears in the scientific report 2016
Database coverage:
Medline ; Clarivate Analytics Master Journal List ; Ebsco Academic Search ; Emerging Sources Citation Index ; Web of Science Core Collection
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The record appears in these collections:
Institute Collections > TÜ DZNE > TÜ DZNE-Tübingen common
Document types > Articles > Journal Article
Institute Collections > TÜ DZNE > TÜ DZNE-AG Maetzler
Institute Collections > TÜ DZNE > TÜ DZNE-AG Gasser
Institute Collections > TÜ DZNE > TÜ DZNE-Ext UKT
Institute Collections > TÜ DZNE > TÜ DZNE-AG Berg
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 Record created 2020-02-18, last modified 2025-04-17


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