guest ::
| Home > Publications Database > Epigenetik – neue Erkenntnisse zum Verständnis neurodegenerativer Erkrankungen | Epigenetic Mechanisms in Neurodegenerative Diseases > print |
| Home > Publications Database > Epigenetik – neue Erkenntnisse zum Verständnis neurodegenerativer Erkrankungen | Epigenetic Mechanisms in Neurodegenerative Diseases > print |
| 001 | 144745 | ||
| 005 | 20240826140055.0 | ||
| 024 | 7 | _ | |a 10.1055/s-0035-1552630 |2 doi |
| 024 | 7 | _ | |a 0302-4350 |2 ISSN |
| 024 | 7 | _ | |a 1431-4886 |2 ISSN |
| 024 | 7 | _ | |a 1438-9428 |2 ISSN |
| 037 | _ | _ | |a DZNE-2020-00195 |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Fischer, A. |0 P:(DE-2719)2000047 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a Epigenetik – neue Erkenntnisse zum Verständnis neurodegenerativer Erkrankungen | Epigenetic Mechanisms in Neurodegenerative Diseases |
| 260 | _ | _ | |a Stuttgart |c 2015 |b Thieme |
| 264 | _ | 1 | |3 online |2 Crossref |b Georg Thieme Verlag KG |c 2015-09-14 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1724673602_18923 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Epigenetics describes the various structures and functions of the DNA-protein matrix (chromatin), which regulate gene expression beyond the DNA sequence. The epigenome determines the differences in the development of genetically identical cells and individuals (mono-zygotic twins). Epigenetic features such as direct biochemical modifications of DNA (methylation) are affected by environmental conditions (famine, early life stress) and are inherited in a modified form, without alteration of the DNA sequence. The analysis of epigenetic processes, in particular DNA methylation, modifications of the DNA-binding proteins, and the functions of the non-coding microRNA, opens an unexpectedly complex field of environment-gene interactions that affect the individual patterns of disease symptoms as well as effects and side effects of many drugs.The study of the epigenome hold the promise of new diagnostic and possibly therapeutic perspectives also for the two most common neurodegenerative diseases, namely Alzheimerʼs and Parkinsonʼs disease. |
| 536 | _ | _ | |a 344 - Clinical and Health Care Research (POF3-344) |0 G:(DE-HGF)POF3-344 |c POF3-344 |f POF III |x 0 |
| 536 | _ | _ | |a 342 - Disease Mechanisms and Model Systems (POF3-342) |0 G:(DE-HGF)POF3-342 |c POF3-342 |f POF III |x 1 |
| 588 | _ | _ | |a Dataset connected to CrossRef |
| 700 | 1 | _ | |a Schneider, A. |0 P:(DE-2719)2812035 |b 1 |u dzne |
| 700 | 1 | _ | |a Wüllner, U. |0 P:(DE-2719)2000056 |b 2 |e Last author |u dzne |
| 773 | 1 | 8 | |a 10.1055/s-0035-1552630 |b : Georg Thieme Verlag KG, 2015-09-14 |n 07 |p 393-401 |3 journal-article |2 Crossref |t Aktuelle Neurologie |v 42 |y 2015 |x 0302-4350 |
| 773 | _ | _ | |a 10.1055/s-0035-1552630 |g Vol. 42, no. 07, p. 393 - 401 |0 PERI:(DE-600)2056721-2 |n 07 |p 393-401 |t Aktuelle Neurologie |v 42 |y 2015 |x 0302-4350 |
| 909 | C | O | |p VDB |o oai:pub.dzne.de:144745 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 0 |6 P:(DE-2719)2000047 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 1 |6 P:(DE-2719)2812035 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 2 |6 P:(DE-2719)2000056 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-344 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Clinical and Health Care Research |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-342 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Disease Mechanisms and Model Systems |x 1 |
| 914 | 1 | _ | |y 2015 |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |d 2019-12-21 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2019-12-21 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2019-12-21 |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0112 |2 StatID |b Emerging Sources Citation Index |d 2019-12-21 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2019-12-21 |
| 920 | 1 | _ | |0 I:(DE-2719)1011302 |k AG Wüllner |l Biomarker Parkinson's Disease |x 0 |
| 920 | 1 | _ | |0 I:(DE-2719)1410002 |k AG Fischer ; AG Fischer |l Epigenetics and Systems Medicine in Neurodegenerative Diseases |x 1 |
| 920 | 1 | _ | |0 I:(DE-2719)1440011 |k AG Schneider Göttingen |l Translational Dementia Research Göttingen |x 2 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-2719)1011302 |
| 980 | _ | _ | |a I:(DE-2719)1410002 |
| 980 | _ | _ | |a I:(DE-2719)1440011 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|