guest ::
| Home > Publications Database > Gait analysis with wearables predicts conversion to parkinson disease. > print |
| Home > Publications Database > Gait analysis with wearables predicts conversion to parkinson disease. > print |
| 001 | 144964 | ||
| 005 | 20250415093352.0 | ||
| 024 | 7 | _ | |a 10.1002/ana.25548 |2 doi |
| 024 | 7 | _ | |a pmid:31294853 |2 pmid |
| 024 | 7 | _ | |a pmc:PMC6899833 |2 pmc |
| 024 | 7 | _ | |a 0364-5134 |2 ISSN |
| 024 | 7 | _ | |a 1531-8249 |2 ISSN |
| 024 | 7 | _ | |a altmetric:63451707 |2 altmetric |
| 037 | _ | _ | |a DZNE-2020-00328 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Del Din, Silvia |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Gait analysis with wearables predicts conversion to parkinson disease. |
| 260 | _ | _ | |a Hoboken, NJ |c 2019 |b Wiley-Blackwell |
| 264 | _ | 1 | |3 online |2 Crossref |b Wiley |c 2019-07-27 |
| 264 | _ | 1 | |3 print |2 Crossref |b Wiley |c 2019-09-01 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1744702396_3743 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Quantification of gait with wearable technology is promising; recent cross-sectional studies showed that gait characteristics are potential prodromal markers for Parkinson disease (PD). The aim of this longitudinal prospective observational study was to establish gait impairments and trajectories in the prodromal phase of PD, identifying which gait characteristics are potentially early diagnostic markers of PD.The 696 healthy controls (mean age = 63 ± 7 years) recruited in the Tubingen Evaluation of Risk Factors for Early Detection of Neurodegeneration study were included. Assessments were performed longitudinally 4 times at 2-year intervals, and people who converted to PD were identified. Participants were asked to walk at different speeds under single and dual tasking, with a wearable device placed on the lower back; 14 validated clinically relevant gait characteristics were quantified. Cox regression was used to examine whether gait at first visit could predict time to PD conversion after controlling for age and sex. Random effects linear mixed models (RELMs) were used to establish longitudinal trajectories of gait and model the latency between impaired gait and PD diagnosis.Sixteen participants were diagnosed with PD on average 4.5 years after first visit (converters; PDC). Higher step time variability and asymmetry of all gait characteristics were associated with a shorter time to PD diagnosis. RELMs indicated that gait (lower pace) deviates from that of non-PDC approximately 4 years prior to diagnosis.Together with other prodromal markers, quantitative gait characteristics can play an important role in identifying prodromal PD and progression within this phase. ANN NEUROL 2019;86:357-367. |
| 536 | _ | _ | |a 344 - Clinical and Health Care Research (POF3-344) |0 G:(DE-HGF)POF3-344 |c POF3-344 |f POF III |x 0 |
| 536 | _ | _ | |a 345 - Population Studies and Genetics (POF3-345) |0 G:(DE-HGF)POF3-345 |c POF3-345 |f POF III |x 1 |
| 542 | _ | _ | |i 2019-07-27 |2 Crossref |u http://creativecommons.org/licenses/by/4.0/ |
| 542 | _ | _ | |i 2019-07-27 |2 Crossref |u http://doi.wiley.com/10.1002/tdm_license_1.1 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 650 | _ | 2 | |a Disease Progression |2 MeSH |
| 650 | _ | 2 | |a Early Diagnosis |2 MeSH |
| 650 | _ | 2 | |a Female |2 MeSH |
| 650 | _ | 2 | |a Gait Analysis |2 MeSH |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Linear Models |2 MeSH |
| 650 | _ | 2 | |a Longitudinal Studies |2 MeSH |
| 650 | _ | 2 | |a Male |2 MeSH |
| 650 | _ | 2 | |a Middle Aged |2 MeSH |
| 650 | _ | 2 | |a Parkinson Disease: diagnosis |2 MeSH |
| 650 | _ | 2 | |a Parkinson Disease: physiopathology |2 MeSH |
| 650 | _ | 2 | |a Prodromal Symptoms |2 MeSH |
| 650 | _ | 2 | |a Prospective Studies |2 MeSH |
| 650 | _ | 2 | |a Time Factors |2 MeSH |
| 650 | _ | 2 | |a Walking |2 MeSH |
| 650 | _ | 2 | |a Wearable Electronic Devices |2 MeSH |
| 700 | 1 | _ | |a Elshehabi, Morad |0 P:(DE-2719)9000064 |b 1 |
| 700 | 1 | _ | |a Galna, Brook |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Hobert, Markus A |0 P:(DE-2719)9000133 |b 3 |
| 700 | 1 | _ | |a Warmerdam, Elke |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Sünkel, Ulrike |0 P:(DE-2719)2811825 |b 5 |u dzne |
| 700 | 1 | _ | |a Brockmann, Kathrin |0 P:(DE-2719)2811916 |b 6 |
| 700 | 1 | _ | |a Metzger, Florian |0 P:(DE-2719)9001194 |b 7 |
| 700 | 1 | _ | |a Hansen, Clint |0 P:(DE-HGF)0 |b 8 |
| 700 | 1 | _ | |a Berg, Daniela |0 P:(DE-2719)2000059 |b 9 |
| 700 | 1 | _ | |a Rochester, Lynn |0 P:(DE-HGF)0 |b 10 |
| 700 | 1 | _ | |a Maetzler, Walter |0 P:(DE-2719)2810915 |b 11 |e Last author |
| 773 | 1 | 8 | |a 10.1002/ana.25548 |b : Wiley, 2019-07-27 |n 3 |p 357-367 |3 journal-article |2 Crossref |t Annals of Neurology |v 86 |y 2019 |x 0364-5134 |
| 773 | _ | _ | |a 10.1002/ana.25548 |g Vol. 86, no. 3, p. 357 - 367 |0 PERI:(DE-600)2037912-2 |n 3 |p 357-367 |t Annals of neurology |v 86 |y 2019 |x 0364-5134 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/144964/files/DZNE-2020-00328_Restricted.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/144964/files/DZNE-2020-00328_Restricted.pdf?subformat=pdfa |x pdfa |
| 909 | C | O | |p VDB |o oai:pub.dzne.de:144964 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 1 |6 P:(DE-2719)9000064 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 3 |6 P:(DE-2719)9000133 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 5 |6 P:(DE-2719)2811825 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 6 |6 P:(DE-2719)2811916 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 7 |6 P:(DE-2719)9001194 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 9 |6 P:(DE-2719)2000059 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 11 |6 P:(DE-2719)2810915 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-344 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Clinical and Health Care Research |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-345 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Population Studies and Genetics |x 1 |
| 914 | 1 | _ | |y 2019 |
| 915 | _ | _ | |a DEAL Wiley |0 StatID:(DE-HGF)3001 |2 StatID |d 2020-02-26 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0160 |2 StatID |b Essential Science Indicators |d 2020-02-26 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1190 |2 StatID |b Biological Abstracts |d 2020-02-26 |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |d 2022-11-30 |w ger |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b ANN NEUROL : 2021 |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |d 2022-11-30 |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |d 2022-11-30 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |d 2022-11-30 |
| 915 | _ | _ | |a IF >= 10 |0 StatID:(DE-HGF)9910 |2 StatID |b ANN NEUROL : 2021 |d 2022-11-30 |
| 920 | 1 | _ | |0 I:(DE-2719)5000024 |k AG Maetzler |l Functional Neurogeriatrics |x 0 |
| 920 | 1 | _ | |0 I:(DE-2719)5000058 |k Ext UKT |l Ext Universitätsklinikum Tübingen |x 1 |
| 920 | 1 | _ | |0 I:(DE-2719)1240005 |k ICRU |l Core ICRU |x 2 |
| 920 | 1 | _ | |0 I:(DE-2719)1210000 |k AG Gasser |l Parkinson Genetics |x 3 |
| 920 | 1 | _ | |0 I:(DE-2719)5000055 |k AG Berg |l Parkinson's Disease Genetics |x 4 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-2719)5000024 |
| 980 | _ | _ | |a I:(DE-2719)5000058 |
| 980 | _ | _ | |a I:(DE-2719)1240005 |
| 980 | _ | _ | |a I:(DE-2719)1210000 |
| 980 | _ | _ | |a I:(DE-2719)5000055 |
| 980 | _ | _ | |a UNRESTRICTED |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26431 |2 Crossref |o 10.1002/mds.26431 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3233/JPD-150685 |2 Crossref |o 10.3233/JPD-150685 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.25844 |2 Crossref |o 10.1002/mds.25844 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1136/jnnp.64.3.314 |2 Crossref |o 10.1136/jnnp.64.3.314 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/ana.22284 |2 Crossref |o 10.1002/ana.22284 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S1353-8020(09)70831-4 |2 Crossref |o 10.1016/S1353-8020(09)70831-4 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/brain/114.5.2283 |2 Crossref |o 10.1093/brain/114.5.2283 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1212/01.wnl.0000340980.19702.6e |2 Crossref |o 10.1212/01.wnl.0000340980.19702.6e |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1136/jnnp.2008.149195 |2 Crossref |o 10.1136/jnnp.2008.149195 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/brain/aws093 |2 Crossref |o 10.1093/brain/aws093 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1212/01.wnl.0000203648.80727.5b |2 Crossref |o 10.1212/01.wnl.0000203648.80727.5b |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.25653 |2 Crossref |o 10.1002/mds.25653 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/ana.22165 |2 Crossref |o 10.1002/ana.22165 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26720 |2 Crossref |o 10.1002/mds.26720 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/gerona/glx254 |2 Crossref |o 10.1093/gerona/glx254 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1186/s12984-016-0154-5 |2 Crossref |o 10.1186/s12984-016-0154-5 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s00415-014-7513-6 |2 Crossref |o 10.1007/s00415-014-7513-6 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s00702-014-1279-y |2 Crossref |o 10.1007/s00702-014-1279-y |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26723 |2 Crossref |o 10.1002/mds.26723 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1186/s12984-016-0136-7 |2 Crossref |o 10.1186/s12984-016-0136-7 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3389/fnagi.2016.00235 |2 Crossref |o 10.3389/fnagi.2016.00235 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1111/ene.12382 |2 Crossref |o 10.1111/ene.12382 |
| 999 | C | 5 | |2 Crossref |o |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1001/archpsyc.1961.01710120031004 |2 Crossref |o 10.1001/archpsyc.1961.01710120031004 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0165-0327(00)00309-8 |2 Crossref |o 10.1016/S0165-0327(00)00309-8 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1097/WAD.0b013e3181b76415 |2 Crossref |o 10.1097/WAD.0b013e3181b76415 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1136/jnnp.56.8.839 |2 Crossref |o 10.1136/jnnp.56.8.839 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.27035 |2 Crossref |o 10.1002/mds.27035 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.25832 |2 Crossref |o 10.1002/mds.25832 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1093/chemse/22.1.39 |2 Crossref |o 10.1093/chemse/22.1.39 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s00405-006-0173-0 |2 Crossref |o 10.1007/s00405-006-0173-0 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.20255 |2 Crossref |o 10.1002/mds.20255 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.25545 |2 Crossref |o 10.1002/mds.25545 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1109/JBHI.2015.2419317 |2 Crossref |o 10.1109/JBHI.2015.2419317 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.12688/f1000research.9591.1 |2 Crossref |o 10.12688/f1000research.9591.1 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0268-0033(98)00089-8 |2 Crossref |o 10.1016/S0268-0033(98)00089-8 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.gaitpost.2012.02.019 |2 Crossref |o 10.1016/j.gaitpost.2012.02.019 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.gaitpost.2009.11.014 |2 Crossref |o 10.1016/j.gaitpost.2009.11.014 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/S0966-6362(02)00190-X |2 Crossref |o 10.1016/S0966-6362(02)00190-X |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1136/bmj.316.7139.1236 |2 Crossref |o 10.1136/bmj.316.7139.1236 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1097/00001648-199001000-00010 |2 Crossref |o 10.1097/00001648-199001000-00010 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3389/fneur.2018.00215 |2 Crossref |o 10.3389/fneur.2018.00215 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/ana.20452 |2 Crossref |o 10.1002/ana.20452 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s00221-007-0955-7 |2 Crossref |o 10.1007/s00221-007-0955-7 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1063/1.3147408 |2 Crossref |o 10.1063/1.3147408 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26110 |2 Crossref |o 10.1002/mds.26110 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s00415-010-5789-8 |2 Crossref |o 10.1007/s00415-010-5789-8 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3389/fnagi.2019.00022 |2 Crossref |o 10.3389/fnagi.2019.00022 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1212/WNL.0000000000003840 |2 Crossref |o 10.1212/WNL.0000000000003840 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/0022-3956(75)90026-6 |2 Crossref |o 10.1016/0022-3956(75)90026-6 |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|