TY  - JOUR
AU  - Jessen, Frank
AU  - Amariglio, Rebecca E
AU  - Buckley, Rachel F
AU  - van der Flier, Wiesje M
AU  - Han, Ying
AU  - Molinuevo, José Luis
AU  - Rabin, Laura
AU  - Rentz, Dorene M
AU  - Rodriguez-Gomez, Octavio
AU  - Saykin, Andrew J
AU  - Sikkes, Sietske A M
AU  - Smart, Colette M
AU  - Wolfsgruber, Steffen
AU  - Wagner, Michael
TI  - The characterisation of subjective cognitive decline.
JO  - The lancet  / Neurology
VL  - 19
IS  - 3
SN  - 1474-4422
CY  - London
PB  - Lancet Publ. Group
M1  - DZNE-2020-01208
SP  - 271 - 278
PY  - 2020
AB  - A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases.
KW  - Alzheimer Disease: diagnosis
KW  - Alzheimer Disease: epidemiology
KW  - Brain
KW  - Cognition: physiology
KW  - Cognitive Dysfunction: diagnosis
KW  - Diagnostic Self Evaluation
KW  - Disease Progression
KW  - Humans
KW  - Neuropsychological Tests
LB  - PUB:(DE-HGF)16
C6  - pmid:31958406
C2  - pmc:PMC7062546
DO  - DOI:10.1016/S1474-4422(19)30368-0
UR  - https://pub.dzne.de/record/151626
ER  -