Journal Article

DZNE-2020-01208

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png The characterisation of subjective cognitive decline.

Jessen, F. (First author)DZNE* ; Amariglio, R. E. ; Buckley, R. F. ; van der Flier, W. M. ; Han, Y. ; Molinuevo, J. L. ; Rabin, L. ; Rentz, D. M. ; Rodriguez-Gomez, O. ; Saykin, A. J. ; Sikkes, S. A. M. ; Smart, C. M. ; Wolfsgruber, S.DZNE* ; Wagner, M. (Last author)DZNE*

2020
Lancet Publ. Group London

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Please use a persistent id in citations: doi:10.1016/S1474-4422(19)30368-0

Abstract: A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases.

Keyword(s): Alzheimer Disease: diagnosis (MeSH) ; Alzheimer Disease: epidemiology (MeSH) ; Brain (MeSH) ; Cognition: physiology (MeSH) ; Cognitive Dysfunction: diagnosis (MeSH) ; Diagnostic Self Evaluation (MeSH) ; Disease Progression (MeSH) ; Humans (MeSH) ; Neuropsychological Tests (MeSH)

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Contributing Institute(s):

1. Clinical Alzheimer’s Disease Research (AG Jessen)
2. Neuropsychology (AG Wagner)
3. Delcode (Delcode)

Research Program(s):

1. 344 - Clinical and Health Care Research (POF3-344) (POF3-344)

Experiment(s):

1. Longitudinal Cognitive Impairment and Dementia Study

Appears in the scientific report 2020

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 50 ; JCR ; SCOPUS ; Web of Science Core Collection

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