000153440 001__ 153440
000153440 005__ 20240425115930.0
000153440 0247_ $$2doi$$a10.1002/mus.27043
000153440 0247_ $$2ISSN$$a0148-639X
000153440 0247_ $$2ISSN$$a1097-4598
000153440 0247_ $$2altmetric$$aaltmetric:97124209
000153440 0247_ $$2pmid$$apmid:32779757
000153440 037__ $$aDZNE-2020-01437
000153440 041__ $$aEnglish
000153440 082__ $$a610
000153440 1001_ $$0P:(DE-2719)9000986$$aSchreiber, Frank$$b0$$eFirst author$$udzne
000153440 245__ $$aTextural markers of ultrasonographic nerve alterations in amyotro phic lateral sclerosis
000153440 260__ $$aNew York, NY [u.a.]$$bWiley$$c2020
000153440 3367_ $$2DRIVER$$aarticle
000153440 3367_ $$2DataCite$$aOutput Types/Journal article
000153440 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1713966596_26794
000153440 3367_ $$2BibTeX$$aARTICLE
000153440 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000153440 3367_ $$00$$2EndNote$$aJournal Article
000153440 520__ $$aUltrasound has revealed cross‐sectional nerve area (CSA) reduction in amyotrophic lateral sclerosis (ALS), but little is known about the sonographic nerve texture beyond CSA alterations. In a large cohort of 177 ALS patients and 57 control subjects, we investigated the covariance and disease‐specific signature of several sonographic texture features of the median and ulnar nerves and their relationship to the patients’ clinical characteristics. ALS patients showed atrophic nerves, a loss of the intranerve structures’ echoic contrast, elevated coarseness, and a trend toward lower cluster shading compared with controls. A reduction in intranerve echoic contrast was related to longer disease duration and poorer functional status in ALS. Sonographic texture markers point toward a significant reorganization of the deep nerve microstructure in ALS. Future studies will be needed to further substantiate the markers’ potential to assess peripheral nerve alterations in ALS.
000153440 536__ $$0G:(DE-HGF)POF3-342$$a342 - Disease Mechanisms and Model Systems (POF3-342)$$cPOF3-342$$fPOF III$$x0
000153440 536__ $$0G:(DE-HGF)POF3-344$$a344 - Clinical and Health Care Research (POF3-344)$$cPOF3-344$$fPOF III$$x1
000153440 588__ $$aDataset connected to CrossRef
000153440 650_2 $$2MeSH$$aAged
000153440 650_2 $$2MeSH$$aAmyotrophic Lateral Sclerosis: diagnostic imaging
000153440 650_2 $$2MeSH$$aAmyotrophic Lateral Sclerosis: pathology
000153440 650_2 $$2MeSH$$aFemale
000153440 650_2 $$2MeSH$$aForearm: innervation
000153440 650_2 $$2MeSH$$aHumans
000153440 650_2 $$2MeSH$$aMale
000153440 650_2 $$2MeSH$$aMedian Nerve: diagnostic imaging
000153440 650_2 $$2MeSH$$aMedian Nerve: pathology
000153440 650_2 $$2MeSH$$aMiddle Aged
000153440 650_2 $$2MeSH$$aUlnar Nerve: diagnostic imaging
000153440 650_2 $$2MeSH$$aUlnar Nerve: pathology
000153440 650_2 $$2MeSH$$aUltrasonography
000153440 650_2 $$2MeSH$$aWit and Humor as Topic
000153440 7001_ $$0P:(DE-2719)2813207$$aGarz, Cornelia$$b1$$udzne
000153440 7001_ $$0P:(DE-2719)2260426$$aHeinze, Hans-Jochen$$b2$$udzne
000153440 7001_ $$00000-0002-9783-8584$$aPetri, Susanne$$b3
000153440 7001_ $$0P:(DE-2719)2000035$$aVielhaber, Stefan$$b4$$udzne
000153440 7001_ $$0P:(DE-2719)2812631$$aSchreiber, Stefanie$$b5$$eLast author$$udzne
000153440 773__ $$0PERI:(DE-600)1476641-3$$a10.1002/mus.27043$$gVol. 62, no. 5, p. 601 - 610$$n5$$p601 - 610$$tMuscle & nerve$$v62$$x1097-4598$$y2020
000153440 8564_ $$uhttps://onlinelibrary.wiley.com/doi/full/10.1002/mus.27043
000153440 8564_ $$uhttps://pub.dzne.de/record/153440/files/DZNE-2020-01437.pdf$$yOpenAccess
000153440 8564_ $$uhttps://pub.dzne.de/record/153440/files/DZNE-2020-01437.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000153440 909CO $$ooai:pub.dzne.de:153440$$popenaire$$popen_access$$pVDB$$pdriver$$pdnbdelivery
000153440 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9000986$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE
000153440 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2813207$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000153440 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2260426$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b2$$kDZNE
000153440 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2000035$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b4$$kDZNE
000153440 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2812631$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b5$$kDZNE
000153440 9131_ $$0G:(DE-HGF)POF3-342$$1G:(DE-HGF)POF3-340$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lErkrankungen des Nervensystems$$vDisease Mechanisms and Model Systems$$x0
000153440 9131_ $$0G:(DE-HGF)POF3-344$$1G:(DE-HGF)POF3-340$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lErkrankungen des Nervensystems$$vClinical and Health Care Research$$x1
000153440 9141_ $$y2020
000153440 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2020-08-23
000153440 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bMUSCLE NERVE : 2021$$d2022-11-29
000153440 915__ $$0LIC:(DE-HGF)CCBYNC4$$2HGFVOC$$aCreative Commons Attribution-NonCommercial CC BY-NC 4.0
000153440 915__ $$0StatID:(DE-HGF)3001$$2StatID$$aDEAL Wiley$$d2020-08-23$$wger
000153440 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2020-08-23
000153440 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000153440 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2020-08-23
000153440 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2022-11-29
000153440 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2022-11-29$$wger
000153440 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-29
000153440 9201_ $$0I:(DE-2719)7000000$$kU Clinical Researchers - Magdeburg$$lU Clinical Researchers - Magdeburg$$x0
000153440 9201_ $$0I:(DE-2719)5000006$$kAG Düzel$$lClinical Neurophysiology and Memory$$x1
000153440 980__ $$ajournal
000153440 980__ $$aVDB
000153440 980__ $$aUNRESTRICTED
000153440 980__ $$aI:(DE-2719)7000000
000153440 980__ $$aI:(DE-2719)5000006
000153440 9801_ $$aFullTexts