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@ARTICLE{Jessen:154273,
author = {Jessen, Frank and Kleineidam, Luca and Wolfsgruber, Steffen
and Bickel, Horst and Brettschneider, Christian and Fuchs,
Angela and Kaduszkiewicz, Hanna and König, Hans-Helmut and
Mallon, Tina and Mamone, Silke and Pabst, Alexander and
Pentzek, Michael and Roehr, Susanne and Weeg, Dagmar and
Jochen, Werle and Weyerer, Siegfried and Wiese, Birgitt and
Maier, Wolfgang and Scherer, Martin and Riedel-Heller,
Steffi and Wagner, Michael},
title = {{P}rediction of dementia of {A}lzheimer type by different
types of subjective cognitive decline.},
journal = {Alzheimer's and dementia},
volume = {16},
number = {12},
issn = {1552-5279},
address = {Hoboken, NJ},
publisher = {Wiley},
reportid = {DZNE-2021-00127},
pages = {1745 - 1749},
year = {2020},
note = {ISSN 1552-5279 not unique: **3 hits**.},
abstract = {Subjective cognitive decline (SCD) is a risk condition for
dementia, including dementia of Alzheimer type (DAT).We
report sensitivity, specificity, positive and negative
predictive values (PPV, NPV) for conversion to all-cause
dementia, and DAT in different SCD types (decline in memory,
assocated worries, longitudinal consitency, of the AgeCoDe
study (n = 2.402, 12 years $follow-up).82.7\%$ of those
converting to any dementia and $84.4\%$ of those converting
with DAT at follow-up, reported memory decline and fulfilled
criteria of SCD at least at one time point before. SCD with
worries at two consecutive time points showed a specificity
of $92.2\%$ for any dementia and also for DAT as well as a
PPV of $44.3\%$ for any dementia and of $36.9\%$ for DAT at
follow-up at the expense of low sensitivity.Different SCD
subtypes were either sensitive or specific for future
all-cause dementia and DAT in cognitively unimpaired
individuals. Modest PPV of the most specific SCD subtypes
were achieved in this low prevalence population.},
keywords = {Alzheimer Disease: classification / Alzheimer Disease:
diagnosis / Alzheimer Disease: epidemiology / Anxiety:
psychology / Cognitive Dysfunction: diagnosis / Cognitive
Dysfunction: epidemiology / Germany: epidemiology / Humans /
Longitudinal Studies / Neuropsychological Tests: statistics
$\&$ numerical data / Predictive Value of Tests / Prevalence
/ Self Report / Alzheimer's disease (Other) / negative
predictive value (Other) / positive predictive value (Other)
/ subjective cognitive decline (Other)},
cin = {AG Jessen / AG Wagner / U Clinical Researchers - Bonn},
ddc = {610},
cid = {I:(DE-2719)1011102 / I:(DE-2719)1011201 /
I:(DE-2719)7000001},
pnm = {344 - Clinical and Health Care Research (POF3-344)},
pid = {G:(DE-HGF)POF3-344},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:33140565},
doi = {10.1002/alz.12163},
url = {https://pub.dzne.de/record/154273},
}