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000154390 037__ $$aDZNE-2021-00243
000154390 041__ $$aEnglish
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000154390 1001_ $$0P:(DE-HGF)0$$aZugman, André$$b0
000154390 245__ $$aMega-analysis methods in ENIGMA: The experience of the generalized anxiety disorder working group.
000154390 260__ $$aNew York, NY$$bWiley-Liss$$c2022
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000154390 520__ $$aThe ENIGMA group on Generalized Anxiety Disorder (ENIGMA-Anxiety/GAD) is part of a broader effort to investigate anxiety disorders using imaging and genetic data across multiple sites worldwide. The group is actively conducting a mega-analysis of a large number of brain structural scans. In this process, the group was confronted with many methodological challenges related to study planning and implementation, between-country transfer of subject-level data, quality control of a considerable amount of imaging data, and choices related to statistical methods and efficient use of resources. This report summarizes the background information and rationale for the various methodological decisions, as well as the approach taken to implement them. The goal is to document the approach and help guide other research groups working with large brain imaging data sets as they develop their own analytic pipelines for mega-analyses.
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000154390 650_7 $$2Other$$adata sharing
000154390 650_7 $$2Other$$ageneralized anxiety disorder
000154390 650_7 $$2Other$$amega-analyses
000154390 650_7 $$2Other$$ameta-analyses
000154390 650_7 $$2Other$$aneuroimaging
000154390 650_2 $$2MeSH$$aAnxiety Disorders: diagnostic imaging
000154390 650_2 $$2MeSH$$aCerebral Cortex: diagnostic imaging
000154390 650_2 $$2MeSH$$aData Interpretation, Statistical
000154390 650_2 $$2MeSH$$aHumans
000154390 650_2 $$2MeSH$$aMeta-Analysis as Topic
000154390 650_2 $$2MeSH$$aMulticenter Studies as Topic: methods
000154390 650_2 $$2MeSH$$aMulticenter Studies as Topic: standards
000154390 650_2 $$2MeSH$$aNeuroimaging: methods
000154390 650_2 $$2MeSH$$aNeuroimaging: standards
000154390 7001_ $$aHarrewijn, Anita$$b1
000154390 7001_ $$aCardinale, Elise M$$b2
000154390 7001_ $$aZwiebel, Hannah$$b3
000154390 7001_ $$aFreitag, Gabrielle F$$b4
000154390 7001_ $$aWerwath, Katy E$$b5
000154390 7001_ $$0P:(DE-HGF)0$$aBas-Hoogendam, Janna M$$b6
000154390 7001_ $$aGroenewold, Nynke A$$b7
000154390 7001_ $$aAghajani, Moji$$b8
000154390 7001_ $$aHilbert, Kevin$$b9
000154390 7001_ $$aCardoner, Narcis$$b10
000154390 7001_ $$aPorta-Casteràs, Daniel$$b11
000154390 7001_ $$aGosnell, Savannah$$b12
000154390 7001_ $$0P:(DE-HGF)0$$aSalas, Ramiro$$b13
000154390 7001_ $$aBlair, Karina S$$b14
000154390 7001_ $$aBlair, James R$$b15
000154390 7001_ $$aHammoud, Mira Z$$b16
000154390 7001_ $$aMilad, Mohammed$$b17
000154390 7001_ $$aBurkhouse, Katie$$b18
000154390 7001_ $$aPhan, K Luan$$b19
000154390 7001_ $$aSchroeder, Heidi K$$b20
000154390 7001_ $$aStrawn, Jeffrey R$$b21
000154390 7001_ $$aBeesdo-Baum, Katja$$b22
000154390 7001_ $$aThomopoulos, Sophia I$$b23
000154390 7001_ $$0P:(DE-2719)2811781$$aGrabe, Hans J$$b24$$udzne
000154390 7001_ $$0P:(DE-2719)9001174$$aVan der Auwera, Sandra$$b25$$udzne
000154390 7001_ $$0P:(DE-2719)2810491$$aWittfeld, Katharina$$b26$$udzne
000154390 7001_ $$aNielsen, Jared A$$b27
000154390 7001_ $$aBuckner, Randy$$b28
000154390 7001_ $$aSmoller, Jordan W$$b29
000154390 7001_ $$aMwangi, Benson$$b30
000154390 7001_ $$aSoares, Jair C$$b31
000154390 7001_ $$aWu, Mon-Ju$$b32
000154390 7001_ $$aZunta-Soares, Giovana B$$b33
000154390 7001_ $$aJackowski, Andrea P$$b34
000154390 7001_ $$aPan, Pedro M$$b35
000154390 7001_ $$aSalum, Giovanni A$$b36
000154390 7001_ $$aAssaf, Michal$$b37
000154390 7001_ $$aDiefenbach, Gretchen J$$b38
000154390 7001_ $$aBrambilla, Paolo$$b39
000154390 7001_ $$aMaggioni, Eleonora$$b40
000154390 7001_ $$0P:(DE-HGF)0$$aHofmann, David$$b41
000154390 7001_ $$aStraube, Thomas$$b42
000154390 7001_ $$0P:(DE-HGF)0$$aAndreescu, Carmen$$b43
000154390 7001_ $$aBerta, Rachel$$b44
000154390 7001_ $$aTamburo, Erica$$b45
000154390 7001_ $$aPrice, Rebecca$$b46
000154390 7001_ $$aManfro, Gisele G$$b47
000154390 7001_ $$aCritchley, Hugo D$$b48
000154390 7001_ $$0P:(DE-HGF)0$$aMakovac, Elena$$b49
000154390 7001_ $$aMancini, Matteo$$b50
000154390 7001_ $$aMeeten, Frances$$b51
000154390 7001_ $$aOttaviani, Cristina$$b52
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000154390 7001_ $$aCanu, Elisa$$b54
000154390 7001_ $$aCividini, Camilla$$b55
000154390 7001_ $$0P:(DE-HGF)0$$aFilippi, Massimo$$b56
000154390 7001_ $$aKostić, Milutin$$b57
000154390 7001_ $$aMunjiza, Ana$$b58
000154390 7001_ $$aFilippi, Courtney A$$b59
000154390 7001_ $$aLeibenluft, Ellen$$b60
000154390 7001_ $$aAlberton, Bianca A V$$b61
000154390 7001_ $$aBalderston, Nicholas L$$b62
000154390 7001_ $$aErnst, Monique$$b63
000154390 7001_ $$aGrillon, Christian$$b64
000154390 7001_ $$aMujica-Parodi, Lilianne R$$b65
000154390 7001_ $$avan Nieuwenhuizen, Helena$$b66
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000154390 7001_ $$aPerino, Michael T$$b77
000154390 7001_ $$aYu, Qiongru$$b78
000154390 7001_ $$aSylvester, Chad M$$b79
000154390 7001_ $$aVeltman, Dick J$$b80
000154390 7001_ $$aLueken, Ulrike$$b81
000154390 7001_ $$aVan der Wee, Nic J A$$b82
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000154390 7001_ $$aJahanshad, Neda$$b84
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000154390 7001_ $$aPine, Daniel S$$b86
000154390 7001_ $$0P:(DE-HGF)0$$aWinkler, Anderson M$$b87
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