Journal Article (Review Article)

DZNE-2021-00243

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Mega-analysis methods in ENIGMA: The experience of the generalized anxiety disorder working group.

Zugman, A. ; Harrewijn, A. ; Cardinale, E. M. ; Zwiebel, H. ; Freitag, G. F. ; Werwath, K. E. ; Bas-Hoogendam, J. M. ; Groenewold, N. A. ; Aghajani, M. ; Hilbert, K. ; Cardoner, N. ; Porta-Casteràs, D. ; Gosnell, S. ; Salas, R. ; Blair, K. S. ; Blair, J. R. ; Hammoud, M. Z. ; Milad, M. ; Burkhouse, K. ; Phan, K. L. ; Schroeder, H. K. ; Strawn, J. R. ; Beesdo-Baum, K. ; Thomopoulos, S. I. ; Grabe, H. J.DZNE* ; Van der Auwera, S.DZNE* ; Wittfeld, K.DZNE* ; Nielsen, J. A. ; Buckner, R. ; Smoller, J. W. ; Mwangi, B. ; Soares, J. C. ; Wu, M.-J. ; Zunta-Soares, G. B. ; Jackowski, A. P. ; Pan, P. M. ; Salum, G. A. ; Assaf, M. ; Diefenbach, G. J. ; Brambilla, P. ; Maggioni, E. ; Hofmann, D. ; Straube, T. ; Andreescu, C. ; Berta, R. ; Tamburo, E. ; Price, R. ; Manfro, G. G. ; Critchley, H. D. ; Makovac, E. ; Mancini, M. ; Meeten, F. ; Ottaviani, C. ; Agosta, F. ; Canu, E. ; Cividini, C. ; Filippi, M. ; Kostić, M. ; Munjiza, A. ; Filippi, C. A. ; Leibenluft, E. ; Alberton, B. A. V. ; Balderston, N. L. ; Ernst, M. ; Grillon, C. ; Mujica-Parodi, L. R. ; van Nieuwenhuizen, H. ; Fonzo, G. A. ; Paulus, M. P. ; Stein, M. B. ; Gur, R. E. ; Gur, R. C. ; Kaczkurkin, A. N. ; Larsen, B. ; Satterthwaite, T. D. ; Harper, J. ; Myers, M. ; Perino, M. T. ; Yu, Q. ; Sylvester, C. M. ; Veltman, D. J. ; Lueken, U. ; Van der Wee, N. J. A. ; Stein, D. J. ; Jahanshad, N. ; Thompson, P. M. ; Pine, D. S. ; Winkler, A. M.

2022
Wiley-Liss New York, NY

This record in other databases:    

Please use a persistent id in citations: doi:10.1002/hbm.25096

Abstract: The ENIGMA group on Generalized Anxiety Disorder (ENIGMA-Anxiety/GAD) is part of a broader effort to investigate anxiety disorders using imaging and genetic data across multiple sites worldwide. The group is actively conducting a mega-analysis of a large number of brain structural scans. In this process, the group was confronted with many methodological challenges related to study planning and implementation, between-country transfer of subject-level data, quality control of a considerable amount of imaging data, and choices related to statistical methods and efficient use of resources. This report summarizes the background information and rationale for the various methodological decisions, as well as the approach taken to implement them. The goal is to document the approach and help guide other research groups working with large brain imaging data sets as they develop their own analytic pipelines for mega-analyses.

Keyword(s): Anxiety Disorders: diagnostic imaging (MeSH) ; Cerebral Cortex: diagnostic imaging (MeSH) ; Data Interpretation, Statistical (MeSH) ; Humans (MeSH) ; Meta-Analysis as Topic (MeSH) ; Multicenter Studies as Topic: methods (MeSH) ; Multicenter Studies as Topic: standards (MeSH) ; Neuroimaging: methods (MeSH) ; Neuroimaging: standards (MeSH) ; data sharing ; generalized anxiety disorder ; mega-analyses ; meta-analyses ; neuroimaging

Note: ISSN 1097-0193 not unique: **3 hits**.

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Contributing Institute(s):

1. Biomarkers of Dementia in the General Population (AG Grabe)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2022

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Database coverage:
; ; ; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DEAL Wiley ; DOAJ Seal ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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