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024 7 _ |a 1097-0193
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037 _ _ |a DZNE-2021-00243
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Zugman, André
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245 _ _ |a Mega-analysis methods in ENIGMA: The experience of the generalized anxiety disorder working group.
260 _ _ |a New York, NY
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520 _ _ |a The ENIGMA group on Generalized Anxiety Disorder (ENIGMA-Anxiety/GAD) is part of a broader effort to investigate anxiety disorders using imaging and genetic data across multiple sites worldwide. The group is actively conducting a mega-analysis of a large number of brain structural scans. In this process, the group was confronted with many methodological challenges related to study planning and implementation, between-country transfer of subject-level data, quality control of a considerable amount of imaging data, and choices related to statistical methods and efficient use of resources. This report summarizes the background information and rationale for the various methodological decisions, as well as the approach taken to implement them. The goal is to document the approach and help guide other research groups working with large brain imaging data sets as they develop their own analytic pipelines for mega-analyses.
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588 _ _ |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
650 _ 7 |a data sharing
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650 _ 7 |a generalized anxiety disorder
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650 _ 7 |a mega-analyses
|2 Other
650 _ 7 |a meta-analyses
|2 Other
650 _ 7 |a neuroimaging
|2 Other
650 _ 2 |a Anxiety Disorders: diagnostic imaging
|2 MeSH
650 _ 2 |a Cerebral Cortex: diagnostic imaging
|2 MeSH
650 _ 2 |a Data Interpretation, Statistical
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Meta-Analysis as Topic
|2 MeSH
650 _ 2 |a Multicenter Studies as Topic: methods
|2 MeSH
650 _ 2 |a Multicenter Studies as Topic: standards
|2 MeSH
650 _ 2 |a Neuroimaging: methods
|2 MeSH
650 _ 2 |a Neuroimaging: standards
|2 MeSH
700 1 _ |a Harrewijn, Anita
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700 1 _ |a Cardinale, Elise M
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700 1 _ |a Zwiebel, Hannah
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700 1 _ |a Freitag, Gabrielle F
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700 1 _ |a Werwath, Katy E
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700 1 _ |a Bas-Hoogendam, Janna M
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700 1 _ |a Groenewold, Nynke A
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700 1 _ |a Aghajani, Moji
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700 1 _ |a Hilbert, Kevin
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700 1 _ |a Cardoner, Narcis
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700 1 _ |a Porta-Casteràs, Daniel
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700 1 _ |a Gosnell, Savannah
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700 1 _ |a Blair, Karina S
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700 1 _ |a Blair, James R
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700 1 _ |a Milad, Mohammed
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700 1 _ |a Burkhouse, Katie
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700 1 _ |a Phan, K Luan
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700 1 _ |a Schroeder, Heidi K
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700 1 _ |a Strawn, Jeffrey R
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700 1 _ |a Beesdo-Baum, Katja
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700 1 _ |a Thomopoulos, Sophia I
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700 1 _ |a Nielsen, Jared A
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700 1 _ |a Buckner, Randy
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700 1 _ |a Smoller, Jordan W
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700 1 _ |a Mwangi, Benson
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700 1 _ |a Soares, Jair C
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700 1 _ |a Wu, Mon-Ju
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700 1 _ |a Zunta-Soares, Giovana B
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700 1 _ |a Jackowski, Andrea P
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700 1 _ |a Pan, Pedro M
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700 1 _ |a Salum, Giovanni A
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700 1 _ |a Assaf, Michal
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700 1 _ |a Diefenbach, Gretchen J
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700 1 _ |a Brambilla, Paolo
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700 1 _ |a Maggioni, Eleonora
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700 1 _ |a Hofmann, David
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700 1 _ |a Straube, Thomas
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700 1 _ |a Andreescu, Carmen
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700 1 _ |a Berta, Rachel
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700 1 _ |a Tamburo, Erica
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700 1 _ |a Price, Rebecca
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700 1 _ |a Manfro, Gisele G
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700 1 _ |a Critchley, Hugo D
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700 1 _ |a Makovac, Elena
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700 1 _ |a Mancini, Matteo
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700 1 _ |a Meeten, Frances
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700 1 _ |a Ottaviani, Cristina
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700 1 _ |a Agosta, Federica
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700 1 _ |a Canu, Elisa
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700 1 _ |a Cividini, Camilla
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700 1 _ |a Filippi, Massimo
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700 1 _ |a Kostić, Milutin
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700 1 _ |a Munjiza, Ana
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700 1 _ |a Filippi, Courtney A
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700 1 _ |a Leibenluft, Ellen
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700 1 _ |a Alberton, Bianca A V
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700 1 _ |a Balderston, Nicholas L
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700 1 _ |a Ernst, Monique
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700 1 _ |a Grillon, Christian
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700 1 _ |a Mujica-Parodi, Lilianne R
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700 1 _ |a van Nieuwenhuizen, Helena
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700 1 _ |a Fonzo, Gregory A
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700 1 _ |a Paulus, Martin P
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700 1 _ |a Stein, Murray B
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700 1 _ |a Gur, Raquel E
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700 1 _ |a Gur, Ruben C
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700 1 _ |a Kaczkurkin, Antonia N
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700 1 _ |a Satterthwaite, Theodore D
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700 1 _ |a Myers, Michael
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700 1 _ |a Perino, Michael T
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700 1 _ |a Yu, Qiongru
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700 1 _ |a Sylvester, Chad M
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700 1 _ |a Veltman, Dick J
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700 1 _ |a Lueken, Ulrike
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700 1 _ |a Van der Wee, Nic J A
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700 1 _ |a Stein, Dan J
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700 1 _ |a Jahanshad, Neda
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700 1 _ |a Thompson, Paul M
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700 1 _ |a Pine, Daniel S
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700 1 _ |a Winkler, Anderson M
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