%0 Journal Article
%A Becker, Sara
%A Pauly, Claire
%A Lawton, Michael
%A Hipp, Geraldine
%A Bowring, Francesca
%A Sulzer, Patricia
%A Hu, Michele
%A Krüger, Rejko
%A Gasser, Thomas
%A Liepelt-Scarfone, Inga
%T Quantifying activities of daily living impairment in Parkinson's disease using the Functional Activities Questionnaire.
%J Neurological sciences
%V 43
%N 2
%@ 1590-3478
%C Milano
%I Springer
%M DZNE-2021-00720
%P 1047-1054
%D 2022
%X Cognitive-driven activity of daily living (ADL) impairment in Parkinson's disease (PD) is increasingly discussed as prodromal marker for dementia. Diagnostic properties of assessments for this specific ADL impairment are sparsely investigated in PD. The ability of the Functional Activities Questionnaire (FAQ) for differentiating between PD patients with normal cognition and with mild cognitive impairment (PD-MCI), according to informant and self-reports, was examined. Global cognitive function in groups with and without mild ADL impairment was compared according to different cut-offs.Multicenter data of 589 patients of an international cohort (CENTRE-PD) were analyzed. Analyses were run separately for informant-rated and self-rated FAQ. Receiver operating characteristic (ROC) analysis was conducted to define the optimal FAQ cut-off for PD-MCI (≥ 1), and groups were additionally split according to reported FAQ cut-offs for PD-MCI in the literature (≥ 3, ≥ 5). Binary logistic regressions examined the effect of the Montreal Cognitive Assessment (MoCA) score in PD patients with and without mild ADL impairment.Two hundred and twenty-five (38.2
%K Activities of Daily Living
%K Cognitive Dysfunction: diagnosis
%K Cognitive Dysfunction: etiology
%K Humans
%K Mental Status and Dementia Tests
%K Neuropsychological Tests
%K Parkinson Disease: complications
%K Parkinson Disease: diagnosis
%K Surveys and Questionnaires
%K Cognitive dysfunction (Other)
%K Cohort studies (Other)
%K Mild cognitive impairment (Other)
%K Neuropsychological tests (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%2 pmc:PMC8789696
%$ pmid:34109514
%R 10.1007/s10072-021-05365-1
%U https://pub.dzne.de/record/155542