AG Becker
Modular High Performance Computing and Artificial Intelligence
Also known as:AG Becker; Modulares Hochleistungsrechnen und künstliche Intelligenz
⇧ BN DZNE ⇧
Recent Publications
All known publications ...
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Journal Article
Feiten, A. F. (First author)DZNE* ; Dahm, K. (First author)DZNE* ; Schlepckow, K. (First author)DZNE* ; van Lengerich, B. ; Suh, J. H. ; Reifschneider, A. ; Wefers, B.DZNE* ; Bartos, L. M. ; Wind, K.Extern* ; de Weerd, L.DZNE* ; Ulas, T.DZNE* ; De-Domenico, E.DZNE* ; Grundschöttel, P.DZNE* ; Paulusch, S.DZNE* ; Tast, B. ; Honda, T. ; Müller, S. A.DZNE* ; Becker, M.DZNE* ; Khalin, I. ; Ricci, A. ; Liesz, A. ; Brunner, B.DZNE* ; Krenner, C.Extern* ; Buschmann, K.Extern* ; Nuscher, B. ; Spieth, L.DZNE* ; Junker, N.DZNE* ; Berghoff, S. A.DZNE* ; Davis, S. S. ; Neher, J. J.DZNE* ; Wurst, W.DZNE* ; Plesnila, N. ; Lewcock, J. W. ; Simons, M.DZNE* ; Lichtenthaler, S. F.DZNE* ; Di Paolo, G. ; Brendel, M.DZNE* ; Capell, A.DZNE* ; Monroe, K. M. ; Schultze, J. L.DZNE* ; Haass, C. (Last author)DZNE*
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.
Nature Communications 17(1), 2002 (2026) [10.1038/s41467-026-68706-8]2026
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Journal Article
Makdissi, N.Extern* ; Hirschmann, D. J. ; Frolov, A.DZNE* ; Sado, I.Extern* ; Bennühr, B. ; Nikolka, F. ; Cheng, J. ; Blank-Stein, N. ; Viola, M. F. ; Yaghmour, M. ; Arnold, P. ; Bonaguro, L.DZNE* ; Becker, M.DZNE* ; Thiele, C. ; Meissner, F. ; Hiller, K. ; Beyer, M. D.DZNE* ; Mass, E. (Last author)DZNE*
Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.
Development 153(2), dev204962 (2026) [10.1242/dev.204962]2026
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Journal Article
Bruno, M. ; Kröger, C.DZNE* ; Ferreira, A. V. ; Zhang, B. ; Röring, R. J. ; Liu, R. ; van der Made, C. I. ; van Rhijn, N. ; Groh, L. ; Klück, V. ; Janssen, N. A. F. ; Li, W. ; Rosati, D. ; Alaswad, A. ; Tercan, H. ; Saiz, J. ; Gonzalez-Riano, C. ; van Uelft, M.DZNE* ; Gaal, O. I. ; Müller, S.DZNE* ; Ferreira, H. J.DZNE* ; Warnat-Herresthal, S.DZNE* ; Becker, M.DZNE* ; Holsten, L.DZNE* ; Kraut, M.DZNE* ; Schulte-Schrepping, J.DZNE* ; Bonaguro, L.DZNE* ; Händler, K.DZNE* ; Cunha, C. ; Schmolz, M. ; Schultze, J. L.DZNE* ; Joosten, L. A. B.DZNE* ; Barbas, C. ; Netea, M. G. ; Li, Y. ; Aschenbrenner, A. C.DZNE* ; Carvalho, A. ; van de Veerdonk, F. L.
Interferon gamma rebalances immunopathological signatures in chronic granulomatous disease through metabolic rewiring.
Blood advances 9(20), 5306 - 5322 (2025) [10.1182/bloodadvances.2025016213]2025
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Sieckmann, K. ; Winnerling, N. ; Silva Ribeiro, D. J. ; Yüksel, S. ; Kardinal, R. ; Steinheuer, L. M. ; Frechen, F. ; Corrêa, L. H. ; Schermann, G. ; Klausen, C. ; Blank-Stein, N. ; Schulte-Schrepping, J.DZNE* ; Osei-Sarpong, C.DZNE* ; Becker, M.DZNE* ; Bonaguro, L.DZNE* ; Beyer, M.DZNE* ; May-Simera, H. L. ; Zurkovic, J. ; Thiele, C. ; Thurley, K. ; Sorokin, L. ; Ruiz de Almodovar, C. ; Mass, E. ; Wachten, D.
BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue.
The EMBO journal 44(19), 5315 - 5336 (2025) [10.1038/s44318-025-00524-y]2025
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Journal Article
Gemünd, I. (First author)DZNE* ; Bonaguro, L.DZNE* ; Becker, M.DZNE* ; Müller, S.DZNE* ; Joos, C. ; De Domenico, E.DZNE* ; Aschenbrenner, A. C.DZNE* ; Schultze, J. L.DZNE* ; Moosmann, A. ; Beyer, M. D. (Last author)DZNE*
Characterization of human CMV-specific CD8+ T cells using multi-layer single-cell omics.
Cell reports / Methods 5(7), 101085 (2025) [10.1016/j.crmeth.2025.101085]2025
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Journal Article
Frolov, A. (First author)DZNE* ; Huang, H. ; Schütz, D. ; Köhne, M. C.DZNE* ; Blank-Stein, N. ; Osei-Sarpong, C.DZNE* ; Büttner, M.DZNE* ; Elmzzahi, T.DZNE* ; Khundadze, M. ; Zahid, M. ; Reuter, M. ; Becker, M.DZNE* ; De Domenico, E.DZNE* ; Bonaguro, L.DZNE* ; Kallies, A. ; Morrison, H. ; Hübner, C. A. ; Händler, K.DZNE* ; Stumm, R. ; Mass, E. ; Beyer, M. D. (Last author)DZNE*
Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15.
Journal of experimental medicine 222(7), e20232357 (2025) [10.1084/jem.20232357]2025
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Journal Article
Ehlers, G. ; Tödtmann, A. M. ; Holsten, L. (First author)DZNE* ; Willers, M. ; Heckmann, J. ; Schöning, J. ; Richter, M. ; Heinemann, A. S. ; Pirr, S. ; Heinz, A. ; Dopfer, C. ; Händler, K.DZNE* ; Becker, M.DZNE* ; Büchel, J. ; Wöckel, A. ; von Kaisenberg, C. ; Hansen, G. ; Hiller, K. ; Schultze, J. L.DZNE* ; Härtel, C. ; Kastenmüller, W. ; Vaeth, M. ; Ulas, T.DZNE* ; Viemann, D.
Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth.
Nature Communications 16(1), 2239 (2025) [10.1038/s41467-025-57357-w]2025
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Software
Oestreich, M. (First author)DZNE* ; Merdivan, E. ; Lee, M.DZNE* ; Schultze, J. L.DZNE* ; Piraud, M. ; Becker, M. (Last author)DZNE*
Model: DrugDiff - small molecule diffusion model with flexible guidance towards molecular properties (v2)
Zenodo (2025) [10.5281/ZENODO.14772460]2025
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Journal Article
Oestreich, M. (First author)DZNE* ; Merdivan, E. ; Lee, M.DZNE* ; Schultze, J. L.DZNE* ; Piraud, M. ; Becker, M. (Last author)DZNE*
DrugDiff: small molecule diffusion model with flexible guidance towards molecular properties.
Journal of cheminformatics 17(1), 23 (2025) [10.1186/s13321-025-00965-x]2025
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Journal Article
Knoll, R. (First author)DZNE* ; Helbig, E. T. ; Dahm, K.DZNE* ; Bolaji, O. ; Hamm, F. ; Dietrich, O. ; van Uelft, M.DZNE* ; Müller, S.DZNE* ; Bonaguro, L.DZNE* ; Schulte-Schrepping, J.DZNE* ; Petrov, L. ; Krämer, B. ; Kraut, M.DZNE* ; Stubbemann, P. ; Thibeault, C. ; Brumhard, S. ; Theis, H.DZNE* ; Hack, G. ; De Domenico, E.DZNE* ; Nattermann, J. ; Becker, M.DZNE* ; Beyer, M. D.DZNE* ; Hillus, D. ; Georg, P. ; Loers, C. ; Tiedemann, J. ; Tober-Lau, P. ; Lippert, L. ; Millet Pascual-Leone, B. ; Tacke, F. ; Rohde, G. ; Suttorp, N. ; Witzenrath, M. ; Group, C. S. (Collaboration Author) ; Group, P. S. (Collaboration Author) ; Saliba, A.-E. ; Ulas, T.DZNE* ; Polansky, J. K. ; Sawitzki, B. ; Sander, L. E. ; Schultze, J. L.DZNE* ; Aschenbrenner, A. C.DZNE* ; Kurth, F.
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.
Cell 187(16), 4318 - 4335.e20 (2024) [10.1016/j.cell.2024.06.014]2024
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All known publications ...
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