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@ARTICLE{Janssen:163604,
      author       = {Janssen, Olin and Jansen, Willemijn J and Vos, Stephanie J
                      B and Boada, Merce and Parnetti, Lucilla and Gabryelewicz,
                      Tomasz and Fladby, Tormod and Molinuevo, José Luis and
                      Villeneuve, Sylvia and Hort, Jakub and Epelbaum, Stéphane
                      and Lleó, Alberto and Engelborghs, Sebastiaan and van der
                      Flier, Wiesje M and Landau, Susan and Popp, Julius and
                      Wallin, Anders and Scheltens, Philip and Rikkert, Marcel
                      Olde and Snyder, Peter J and Rowe, Chris and Chételat,
                      Gaël and Ruíz, Agustin and Marquié, Marta and Chipi,
                      Elena and Wolfsgruber, Steffen and Heneka, Michael and
                      Boecker, Henning and Peters, Oliver and Jarholm, Jonas and
                      Rami, Lorena and Tort-Merino, Adrià and Binette, Alexa
                      Pichet and Poirier, Judes and Rosa-Neto, Pedro and Cerman,
                      Jiri and Dubois, Bruno and Teichmann, Marc and Alcolea,
                      Daniel and Fortea, Juan and Sánchez-Saudinós, M Belén and
                      Ebenau, Jarith and Pocnet, Cornelia and Eckerström, Marie
                      and Thompson, Louisa and Villemagne, Victor and Buckley,
                      Rachel and Burnham, Samantha and Delarue, Marion and
                      Freund-Levi, Yvonne and Wallin, Åsa K and Ramakers, Inez
                      and Tsolaki, Magda and Soininen, Hilkka and Hampel, Harald
                      and Spiru, Luiza and Tijms, Betty and Ossenkoppele, Rik and
                      Verhey, Frans R J and Jessen, Frank and Visser, Pieter
                      Jelle},
      collaboration = {Initiative, Alzheimer's Disease Neuroimaging and group,
                      FACEHBI study and group, PREVENT-AD research},
      title        = {{C}haracteristics of subjective cognitive decline
                      associated with amyloid positivity.},
      journal      = {Alzheimer's and dementia},
      volume       = {18},
      number       = {10},
      issn         = {1552-5260},
      address      = {Hoboken, NJ},
      publisher    = {Wiley},
      reportid     = {DZNE-2022-00350},
      pages        = {1832-1845},
      year         = {2022},
      note         = {(CC BY-NC)},
      abstract     = {The evidence for characteristics of persons with subjective
                      cognitive decline (SCD) associated with amyloid positivity
                      is limited.In 1640 persons with SCD from 20 Amyloid
                      Biomarker Study cohort, we investigated the associations of
                      SCD-specific characteristics (informant confirmation,
                      domain-specific complaints, concerns, feelings of worse
                      performance) demographics, setting, apolipoprotein E gene
                      (APOE) ε4 carriership, and neuropsychiatric symptoms with
                      amyloid positivity.Between cohorts, amyloid positivity in
                      70-year-olds varied from $10\%$ to $76\%.$ Only older age,
                      clinical setting, and APOE ε4 carriership showed univariate
                      associations with increased amyloid positivity. After
                      adjusting for these, lower education was also associated
                      with increased amyloid positivity. Only within a research
                      setting, informant-confirmed complaints, memory complaints,
                      attention/concentration complaints, and no depressive
                      symptoms were associated with increased amyloid positivity.
                      Feelings of worse performance were associated with less
                      amyloid positivity at younger ages and more at older
                      ages.Next to age, setting, and APOE ε4 carriership,
                      SCD-specific characteristics may facilitate the
                      identification of amyloid-positive individuals.},
      keywords     = {Humans / Amyloid / Amyloidogenic Proteins / Amyloidosis /
                      Apolipoprotein E4: genetics / Biomarkers / Brain: metabolism
                      / Cognitive Dysfunction: genetics / Cognitive Dysfunction:
                      psychology / Positron-Emission Tomography / Alzheimer's
                      disease (Other) / amyloid (Other) / cerebrospinal fluid
                      (Other) / positron emission tomography (Other) / subjective
                      cognitive decline (Other)},
      cin          = {AG Wagner / AG Jessen / Delcode},
      ddc          = {610},
      cid          = {I:(DE-2719)1011201 / I:(DE-2719)1011102 /
                      I:(DE-2719)5000034},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      experiment   = {EXP:(DE-2719)DELCODE-20140101},
      typ          = {PUB:(DE-HGF)16},
      pmc          = {pmc:PMC9786747},
      pubmed       = {pmid:34877782},
      doi          = {10.1002/alz.12512},
      url          = {https://pub.dzne.de/record/163604},
}