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@ARTICLE{Wagemann:163951,
author = {Wagemann, Olivia and Loosli, Sandra V and Vöglein,
Jonathan and Prix, Catharina and Wlasich, Elisabeth and
Nuebling, Georg Sebastian Otto and Danek, Adrian and Levin,
Johannes},
title = {{R}egression bei jungen {E}rwachsenen mit einem
{D}own-{S}yndrom: {E}ine {F}allserie.},
journal = {Fortschritte der Neurologie, Psychiatrie},
volume = {90},
number = {10},
issn = {0015-8194},
address = {Stuttgart [u.a.]},
publisher = {Thieme},
reportid = {DZNE-2022-00625},
pages = {465-470},
year = {2022},
abstract = {Regression in young adults with Down syndrome can present
itself with an acute loss of acquired skills and change in
behavior. The aim of our case series was to describe the
heterogeneous clinical presentation of this syndrome as well
as accompanying diagnostic and therapeutic challenges and
consequences.All three patients were assessed with the
CAMDEX-DS (Cambridge Examination for Mental Disorders of
Older People with Down Syndrome and Others with Intellectual
Disabilities) and the criteria published by the DSMIG-USA
(Down-Syndrome Medical Interest Group USA).After ruling out
somatic or other psychiatric causes, the application of the
DSMIG-USA criteria resulted in diagnosing at least a
probable unexplained regression in all three patients.The
thorough diagnostic investigation of unexplained acute
regression in young adults with Down syndrome allows for
quick initiation of therapeutic and supportive measures.
Using the DMSIG-USA criteria facilitates the assessment of
the underlying diffuse and heterogenous pathology.},
keywords = {Aged / Cognition / Down Syndrome: complications / Humans /
Intellectual Disability: complications / Young Adult},
cin = {AG Höglinger 1 / AG Höglinger 2 / Clinical Dementia
Research München},
ddc = {150},
cid = {I:(DE-2719)1110002 / I:(DE-2719)1111015 /
I:(DE-2719)1111016},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:35405744},
doi = {10.1055/a-1743-2915},
url = {https://pub.dzne.de/record/163951},
}