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| Home > Publications Database > Regression bei jungen Erwachsenen mit einem Down-Syndrom: Eine Fallserie. |
| Home > Publications Database > Regression bei jungen Erwachsenen mit einem Down-Syndrom: Eine Fallserie. |
| Journal Article | DZNE-2022-00625 |
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2022
Thieme
Stuttgart [u.a.]
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Please use a persistent id in citations: doi:10.1055/a-1743-2915
Abstract: Regression in young adults with Down syndrome can present itself with an acute loss of acquired skills and change in behavior. The aim of our case series was to describe the heterogeneous clinical presentation of this syndrome as well as accompanying diagnostic and therapeutic challenges and consequences.All three patients were assessed with the CAMDEX-DS (Cambridge Examination for Mental Disorders of Older People with Down Syndrome and Others with Intellectual Disabilities) and the criteria published by the DSMIG-USA (Down-Syndrome Medical Interest Group USA).After ruling out somatic or other psychiatric causes, the application of the DSMIG-USA criteria resulted in diagnosing at least a probable unexplained regression in all three patients.The thorough diagnostic investigation of unexplained acute regression in young adults with Down syndrome allows for quick initiation of therapeutic and supportive measures. Using the DMSIG-USA criteria facilitates the assessment of the underlying diffuse and heterogenous pathology.
Keyword(s): Aged (MeSH) ; Cognition (MeSH) ; Down Syndrome: complications (MeSH) ; Humans (MeSH) ; Intellectual Disability: complications (MeSH) ; Young Adult (MeSH)
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