Contribution to a book

DZNE-2022-01062

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Postsynaptic Density/Architecture at Excitatory Synapses ☆

Kornau, H.-C. (First author)DZNE*

2017
Elsevier
ISBN: 978-012809324-5

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Please use a persistent id in citations: doi:10.1016/B978-0-12-809324-5.02357-9

Abstract: At excitatory synapses of the central nervous system, the postsynaptic density (PSD), a specialized structure underneath the postsynaptic membrane, controls the reception and integration of synaptic signals. The PSD functions as an extended protein assembly connecting integral membrane proteins (e.g., glutamate-gated ion channels) with cytoskeletal elements and signaling molecules via an ordered array of scaffolding proteins. Synaptic activity can adjust size and composition of the PSD, contributing to changes in synaptic strength.

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Contributing Institute(s):

1. Network Dysfunction (AG Schmitz 1)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2017

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