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@INBOOK{Posch:164600,
author = {Brosseron, Frederic and Marcus, Katrin and May, Caroline},
editor = {Posch, Anton},
title = {{I}solating {P}eripheral {L}ymphocytes by {D}ensity
{G}radient {C}entrifugation and {M}agnetic {C}ell {S}orting},
volume = {1295},
address = {New York, NY},
publisher = {Springer New York},
reportid = {DZNE-2022-01143},
isbn = {978-1-4939-2549-0 (print)},
series = {Methods in Molecular Biology},
pages = {33 - 42},
year = {2015},
comment = {Proteomic Profiling / Posch, Anton (Editor) ; New York, NY
: Springer New York, 2015, Chapter 3 ; ISSN:
1064-3745=1940-6029 ; ISBN:
978-1-4939-2549-0=978-1-4939-2550-6 ;
doi:10.1007/978-1-4939-2550-6},
booktitle = {Proteomic Profiling / Posch, Anton
(Editor) ; New York, NY : Springer New
York, 2015, Chapter 3 ; ISSN:
1064-3745=1940-6029 ; ISBN:
978-1-4939-2549-0=978-1-4939-2550-6 ;
doi:10.1007/978-1-4939-2550-6},
abstract = {Combining density gradient centrifugation with magnetic
cell sorting provides a powerful tool to isolate blood cells
with high reproducibility, yield, and purity. It also allows
for subsequent separation of multiple cell types, resulting
in the possibility to analyze different purified fractions
from one donor’s sample. The centrifugation step divides
whole blood into peripheral blood mononuclear cells (PBMC),
erythrocytes, and platelet-rich plasma. In the following,
lymphocyte subtypes can be consecutively isolated from the
PBMC fraction. This chapter describes enrichment of
erythrocytes, CD14-positive monocytes and CD3-positive T
lymphocytes. Alternatively, other cell types can be targeted
by using magnetic beads specific for the desired
subpopulation.},
keywords = {Antigens, CD: metabolism / Centrifugation, Density
Gradient: methods / Flow Cytometry: methods / Humans /
Immunomagnetic Separation: methods / Immunophenotyping /
Leukocytes, Mononuclear: cytology / Leukocytes, Mononuclear:
metabolism / Lymphocytes: cytology / Lymphocytes:
metabolism},
cin = {AG Heneka1 ; AG Heneka 1},
ddc = {570},
cid = {I:(DE-2719)1011301},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
typ = {PUB:(DE-HGF)7},
pubmed = {pmid:25820711},
doi = {10.1007/978-1-4939-2550-6_3},
url = {https://pub.dzne.de/record/164600},
}