Journal Article

DZNE-2022-01204

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance.

Stern, Y. ; Arenaza-Urquijo, E. M. ; Bartrés-Faz, D. ; Belleville, S. ; Cantilon, M. ; Chetelat, G. ; Ewers, M.Extern* ; Franzmeier, N. ; Kempermann, G.DZNE* ; Kremen, W. S. ; Okonkwo, O. ; Scarmeas, N. ; Soldan, A. ; Udeh-Momoh, C. ; Valenzuela, M. ; Vemuri, P. ; Vuoksimaa, E. ; the Reserve, R. a. P. F. P. E. D. ; Workgroup, C. F. (Collaboration Author)

2020
Wiley Hoboken, NJ

This record in other databases:    

Please use a persistent id in citations: doi:10.1016/j.jalz.2018.07.219

Abstract: Several concepts, which in the aggregate get might be used to account for 'resilience' against age- and disease-related changes, have been the subject of much research. These include brain reserve, cognitive reserve, and brain maintenance. However, different investigators have use these terms in different ways, and there has never been an attempt to arrive at consensus on the definition of these concepts. Furthermore, there has been confusion regarding the measurement of these constructs and the appropriate ways to apply them to research. Therefore the reserve, resilience, and protective factors professional interest area, established under the auspices of the Alzheimer's Association, established a whitepaper workgroup to develop consensus definitions for cognitive reserve, brain reserve, and brain maintenance. The workgroup also evaluated measures that have been used to implement these concepts in research settings and developed guidelines for research that explores or utilizes these concepts. The workgroup hopes that this whitepaper will form a reference point for researchers in this area and facilitate research by supplying a common language.

Keyword(s): Aging: physiology (MeSH) ; Alzheimer Disease (MeSH) ; Brain: physiology (MeSH) ; Cognitive Reserve (MeSH) ; Guidelines as Topic: standards (MeSH) ; Humans (MeSH) ; Research Design (MeSH) ; Alzheimer's disease ; Cognition ; Epidemiology ; Functional imaging ; Structural imaging

---

Contributing Institute(s):

1. Adult Neurogenesis (AG Kempermann 1)

Research Program(s):

1. 342 - Disease Mechanisms and Model Systems (POF3-342) (POF3-342)

Appears in the scientific report 2020

---

Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Wiley ; Essential Science Indicators ; IF >= 15 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---