TY  - CHART
AU  - Kuehn, Esther
AU  - Liu, Peng
AU  - Chrysidou, Anastasia
AU  - Doehler, Juliane
AU  - Wolbers, Thomas
TI  - Dataset: The organizational principles of de-differentiated topographic maps - Data
PB  - Dryad
M1  - DZNE-2022-01782
PY  - 2020
AB  - Topographic maps are a fundamental feature of cortex architecture in the mammalian brain. One common theory is that the de-differentiation of topographic maps links to impairments in everyday behavior due to less precise functional map readouts. Here, we tested this theory by characterizing de-differentiated topographic maps in primary somatosensory cortex (SI) of younger and older adults by means of ultra-high resolution functional magnetic resonance imaging together with perceptual finger individuation and hand dexterity. Older adults’ SI maps showed similar amplitude, size, and levels of stimulus-related noise than younger adults’ SI maps, but presented with less representational similarity between distant fingers. Larger population receptive field sizes in older adults’ maps did not correlate with behavior, whereas reduced cortical distances related to better hand dexterity. Our data uncover the drawbacks of a simple de-differentiation model of topographic map function, and motivate the introduction of a feature-based model of cortical reorganization.
LB  - PUB:(DE-HGF)32
DO  - DOI:10.5061/dryad.mgqnk98x8
UR  - https://pub.dzne.de/record/169075
ER  -