Dataset

DZNE-2022-01782

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dataset: The organizational principles of de-differentiated topographic maps - Data

Kuehn, E.Extern* ; Liu, P.Extern* ; Chrysidou, A.Extern* ; Doehler, J. ; Wolbers, T. (Last author)DZNE*

2020
Dryad

This record in other databases:  

Please use a persistent id in citations: doi:10.5061/DRYAD.MGQNK98X8  doi:10.5061/dryad.mgqnk98x8

Abstract: Topographic maps are a fundamental feature of cortex architecture in the mammalian brain. One common theory is that the de-differentiation of topographic maps links to impairments in everyday behavior due to less precise functional map readouts. Here, we tested this theory by characterizing de-differentiated topographic maps in primary somatosensory cortex (SI) of younger and older adults by means of ultra-high resolution functional magnetic resonance imaging together with perceptual finger individuation and hand dexterity. Older adults’ SI maps showed similar amplitude, size, and levels of stimulus-related noise than younger adults’ SI maps, but presented with less representational similarity between distant fingers. Larger population receptive field sizes in older adults’ maps did not correlate with behavior, whereas reduced cortical distances related to better hand dexterity. Our data uncover the drawbacks of a simple de-differentiation model of topographic map function, and motivate the introduction of a feature-based model of cortical reorganization.

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Contributing Institute(s):

1. Aging, Cognition and Technology (AG Wolbers)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2020

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Linked articles:

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Liu, P. (First author)DZNE* ; Chrysidou, A.DZNE* ; Döhler, J.DZNE* ; Hebart, M. N. ; Wolbers, T.DZNE* ; Kuehn, E. (Last author)DZNE*
The organizational principles of de-differentiated topographic maps in somatosensory cortex.
eLife 10, e60090 (2021) [10.7554/eLife.60090]2021   Files  Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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