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@MISC{Holstege:169098,
author = {Holstege, Henne and Hulsman, Marc and Charbonnier, Camille
and Grenier-Boley, Benjamin and Quenez, Olivier and Grozeva,
Detelina and van Rooij, Jeroen G. J. and Sims, Rebecca and
Ahmad, Shahzad and Amin, Najaf and Norsworthy, Penny J. and
Dols-Icardo, Oriol and Hummerich, Holger and Kawalia, Amit
and Amouyel, Philippe and Beecham, Gary W. and Berr,
Claudine and Bis, Joshua C. and Boland, Anne and Bossù,
Paola and Bouwman, Femke and Bras, Jose and Campion,
Dominique and Nicholas Cochran, J. and Daniele, Antonio and
Dartigues, Jean-François and Debette, Stéphanie and
Deleuze, Jean-François and Denning, Nicola and DeStefano,
Anita L and Farrer, Lindsay A. and Fernandez, Maria Victoria
and Fox, Nick C. and Galimberti, Daniela and Genin,
Emmanuelle and Gille, Hans and Guen, Yann Le and Guerreiro,
Rita and Haines, Jonathan L. and Holmes, Clive and Arfan
Ikram, M. and Kamran Ikram, M. and Jansen, Iris and Kraaij,
Robert and Lathrop, Marc and Lemstra, Afina W. and Lleó,
Alberto and Luckcuck, Lauren and Mannens, Marcel M. A. M.
and Marshall, Rachel and Martin, Eden R and Masullo, Carlo
and Mayeux, Richard and Mecocci, Patrizia and Meggy, Alun
and Mol, Merel O. and Morgan, Kevin and Myers, Richard M.
and Nacmias, Benedetta and Naj, Adam C and Napolioni,
Valerio and Pasquier, Florence and Pastor, Pau and
Pericak-Vance, Margaret A. and Raybould, Rachel and Redon,
Richard and Reinders, Marcel J. T. and Richard, Anne-Claire
and Riedel-Heller, Steffi G and Rivadeneira, Fernando and
Rousseau, Stéphane and Ryan, Natalie S. and Saad, Salha and
Sanchez-Juan, Pascual and Schellenberg, Gerard D. and
Scheltens, Philip and Schott, Jonathan M. and Seripa, Davide
and Seshadri, Sudha and Sie, Daoud and Sistermans, Erik and
Sorbi, Sandro and Spaendonk, Resie van and Spalletta,
Gianfranco and Tesi, Niccólo and Tijms, Betty and
Uitterlinden, André G and van der Lee, Sven J. and Visser,
Pieter Jelle de and Wagner, Michael and Wallon, David and
Wang, Li-San and Zarea, Aline and Clarimon, Jordi and van
Swieten, John C. and Greicius, Michael and Yokoyama,
Jennifer S. and Cruchaga, Carlos and Hardy, John and
Ramirez, Alfredo and Mead, Simon and van der Flier, Wiesje
M. and Duijn, Cornelia M van and Williams, Julie and
Nicolas, Gaël and Bellenguez, Céline and Lambert,
Jean-Charles},
othercontributors = {database, Alzheimer's Disease Neuroimaging Initiative},
title = {{D}ataset: {S}ummary statistics for '{E}xome sequencing
identifies rare damaging variants in {ATP}8{B}4 and {ABCA}1
as risk factors for {A}lzheimer's {D}isease'},
publisher = {Zenodo},
reportid = {DZNE-2022-01805},
year = {2022},
abstract = {These are the burden test results (summary statistics) for
the publication: 'Exome sequencing identifies rare damaging
variants in ATP8B4 and ABCA1 as risk factors for
Alzheimer’s Disease', Nature Genetics, 2022. Format:
tab-separated-value. Fields: $gene_stable_id:$ Ensembl gene
id $gene_name:$ standard gene name pvalue: burden test
significance (likelihood ratio test, population structure
correction based on 6 PCA components) $cmac_all:$ sum of
minor allele dosages across all contributing samples and
variants group: variant group (LOF, LOF+REVEL>=75,
LOF+REVEL>=50, LOF+REVEL>=25, see publication methods for
further selection criteria). beta/se: beta/se of logistic
ordinal regression (see publication methods). Positive =
risk-increasing. Negative = risk-decreasing.},
keywords = {Alzheimer's disease (Other) / Exome sequencing (Other) /
Burden test (Other)},
cin = {Patient Studies Bonn / AG Wagner},
cid = {I:(DE-2719)1011101 / I:(DE-2719)1011201},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)32},
doi = {10.5281/zenodo.6818051},
url = {https://pub.dzne.de/record/169098},
}