%0 Journal Article
%A Perez, Maria Jose
%A Deleidi, Michela
%T New insights into the autophagy-NAD axis in brain disease.
%J Cell reports
%V 42
%N 5
%@ 2211-1247
%C [New York, NY]
%I Elsevier
%M DZNE-2023-00486
%P 112420
%D 2023
%X Sun et al. demonstrate that defects in autophagy cause nicotinamide adenine dinucleotide (NAD) depletion and neurotoxicity.1 Restoring NAD levels rescues cytotoxicity in autophagy-deficient neurons, providing a potential therapy for neurodegenerative and lysosomal storage diseases associated with autophagy defects.
%K Humans
%K NAD
%K Brain Diseases
%K Neurons
%K Autophagy
%K CP: Cell biology (Other)
%K CP: Metabolism (Other)
%K NAD (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37083331
%R 10.1016/j.celrep.2023.112420
%U https://pub.dzne.de/record/257689