TY  - JOUR
AU  - Perez, Maria Jose
AU  - Deleidi, Michela
TI  - New insights into the autophagy-NAD axis in brain disease.
JO  - Cell reports
VL  - 42
IS  - 5
SN  - 2211-1247
CY  - [New York, NY]
PB  - Elsevier
M1  - DZNE-2023-00486
SP  - 112420
PY  - 2023
AB  - Sun et al. demonstrate that defects in autophagy cause nicotinamide adenine dinucleotide (NAD) depletion and neurotoxicity.1 Restoring NAD levels rescues cytotoxicity in autophagy-deficient neurons, providing a potential therapy for neurodegenerative and lysosomal storage diseases associated with autophagy defects.
KW  - Humans
KW  - NAD
KW  - Brain Diseases
KW  - Neurons
KW  - Autophagy
KW  - CP: Cell biology (Other)
KW  - CP: Metabolism (Other)
KW  - NAD (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:37083331
DO  - DOI:10.1016/j.celrep.2023.112420
UR  - https://pub.dzne.de/record/257689
ER  -