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@ARTICLE{Kapadia:266741,
author = {Kapadia, Akshay and Theil, Sandra and Opitz, Sabine and
Villacampa, Nàdia and Beckert, Hannes and Schoch, Susanne
and Heneka, Michael T and Kumar, Sathish and Walter, Jochen},
title = {{P}hosphorylation-state dependent intraneuronal sorting of
{A}β differentially impairs autophagy and the
endo-lysosomal system.},
journal = {Autophagy},
volume = {20},
number = {1},
issn = {1554-8627},
address = {Abingdon, Oxon},
publisher = {Taylor $\&$ Francis},
reportid = {DZNE-2024-00004},
pages = {166 - 187},
year = {2024},
abstract = {AD: Alzheimer disease; APP: amyloid beta precursor protein;
ATG: autophagy related; Aβ: amyloid-β; CTSD: cathepsin D;
DAPI: 4',6-diamidino-2-phenylindole; EEA1: early endosome
antigen 1; FA: formic acid; GFP: green fluorescent protein;
LAMP2: lysosomal-associated membrane protein 2; MAP1LC3/LC3:
microtubule-associated protein 1 light chain 3; MAP2:
microtubule-associated protein 2; nmAβ: non-modified
amyloid-β; npAβ: non-phosphorylated amyloid-β; pAβ:
phosphorylated amyloid-β; p-Ser26Aβ: amyloid-β
phosphorylated at serine residue 26; p-Ser8Aβ: amyloid-β
phosphorylated at serine residue 8; RAB: RAB, member RAS
oncogene family; RFP: red fluorescent protein; SQSTM1/p62:
sequestome 1; YFP: yellow fluorescent protein.},
keywords = {Autophagy: physiology / Amyloid beta-Peptides: metabolism /
Phosphorylation / Green Fluorescent Proteins: metabolism /
Lysosomes: metabolism / Serine / Alzheimer’s disease
(Other) / Alzheimer’s disease (Other) / Alzheimer’s
disease (Other) / Alzheimer’s disease (Other) / autophagic
flux (Other) / neurodegeneration (Other) / phosphorylated
Aβ (Other) / post-translationally modified Aβ (Other) /
vesicular trafficking (Other) / Amyloid beta-Peptides (NLM
Chemicals) / Green Fluorescent Proteins (NLM Chemicals) /
Serine (NLM Chemicals) / phosphorylated Aβ (Other) /
post-translationally modified Aβ (Other) / phosphorylated
Aβ (Other) / post-translationally modified Aβ (Other) /
phosphorylated Aβ (Other) / post-translationally modified
Aβ (Other)},
cin = {AG Heneka ; AG Heneka / Tech Transfer},
ddc = {570},
cid = {I:(DE-2719)1011303 / I:(DE-2719)1030028},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:37642583},
pmc = {pmc:PMC10761119},
doi = {10.1080/15548627.2023.2252300},
url = {https://pub.dzne.de/record/266741},
}