TY - JOUR AU - Bohmbach, Kirsten AU - Henneberger, Christian TI - Activity-induced reactivity of astrocytes impairs cognition. JO - PLoS biology VL - 22 IS - 7 SN - 1544-9173 CY - Lawrence, KS PB - PLoS M1 - DZNE-2024-00806 SP - e3002712 PY - 2024 AB - Glial cells such as astrocytes can modulate neuronal signaling. Astrocytes can also acquire a reactive phenotype that correlates with cognitive impairments in brain diseases. A study in PLOS Biology shows that prolonged activation of astrocytes can trigger both cognitive impairments and a reactive astrocyte phenotype. KW - Astrocytes: physiology KW - Animals KW - Humans KW - Cognition: physiology KW - Cognitive Dysfunction: physiopathology KW - Neurons: physiology LB - PUB:(DE-HGF)16 C6 - pmid:38996200 C2 - pmc:PMC11245315 DO - DOI:10.1371/journal.pbio.3002712 UR - https://pub.dzne.de/record/270634 ER -