Journal Article (Editorial)

DZNE-2024-00806

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Activity-induced reactivity of astrocytes impairs cognition.

Bohmbach, K. ; Henneberger, C. (Last author)DZNE*

2024
PLoS Lawrence, KS

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Please use a persistent id in citations: doi:10.1371/journal.pbio.3002712

Abstract: Glial cells such as astrocytes can modulate neuronal signaling. Astrocytes can also acquire a reactive phenotype that correlates with cognitive impairments in brain diseases. A study in PLOS Biology shows that prolonged activation of astrocytes can trigger both cognitive impairments and a reactive astrocyte phenotype.

Keyword(s): Astrocytes: physiology (MeSH) ; Animals (MeSH) ; Humans (MeSH) ; Cognition: physiology (MeSH) ; Cognitive Dysfunction: physiopathology (MeSH) ; Neurons: physiology (MeSH)

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Contributing Institute(s):

1. Synaptic and Glial Plasticity (AG Henneberger)

Research Program(s):

1. 351 - Brain Function (POF4-351) (POF4-351)

Appears in the scientific report 2024

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