000272137 001__ 272137
000272137 005__ 20250127091538.0
000272137 0247_ $$2pmc$$apmc:PMC11393326
000272137 0247_ $$2doi$$a10.1038/s41598-024-72040-8
000272137 0247_ $$2pmid$$apmid:39266690
000272137 0247_ $$2altmetric$$aaltmetric:167423073
000272137 037__ $$aDZNE-2024-01132
000272137 041__ $$aEnglish
000272137 082__ $$a600
000272137 1001_ $$0P:(DE-2719)9002130$$aAndac, Safa$$b0$$udzne
000272137 245__ $$aNavigation performance in glaucoma: virtual-reality-based assessment of path integration.
000272137 260__ $$a[London]$$bMacmillan Publishers Limited, part of Springer Nature$$c2024
000272137 3367_ $$2DRIVER$$aarticle
000272137 3367_ $$2DataCite$$aOutput Types/Journal article
000272137 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1727089444_16291
000272137 3367_ $$2BibTeX$$aARTICLE
000272137 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000272137 3367_ $$00$$2EndNote$$aJournal Article
000272137 520__ $$aNavigation is essential for moving between locations in our daily lives. We investigated the relationship between visual impairment in glaucoma and path-integration-based navigation. Fourteen glaucoma and 15 controls underwent ophthalmological examination (including visual acuity (logMAR), visual field sensitivity (MD: mean deviation from matched reference cohort), and peripapillary retinal nerve fiber layer (pRNFL)). Both groups navigated physically in virtual reality (VR) environments during daylight and dawn conditions. Briefly, the participants traversed a path marked by three targets, subsequently pointing back to the path's origin. Outcome measures included (i) travel-time, (ii) pointing-time, and (iii) Euclidian-distance error between indicated and starting position. Robust linear regression was conducted between visual function outcomes of the better eye and VR outcome measures. Glaucoma patients showed increase in travel-time (by 8.2 ± 1.7 s; p = 0.002) and in pointing-time (by 5.3 ± 1.6 s; p = 0.016). Predictors were MD for all outcome measures (p < 0.01) and pRNFL for travel-time (p < 0.01). The results suggest that the effect of glaucoma on the elapsed time depends on disease progression, i.e. people with stronger visual impairment need more time. This uncertainty during everyday navigation tasks may adversely affect their quality of life.
000272137 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0
000272137 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
000272137 650_7 $$2Other$$aGlaucoma
000272137 650_7 $$2Other$$aNavigation
000272137 650_7 $$2Other$$aPath integration
000272137 650_7 $$2Other$$aVirtual reality
000272137 650_7 $$2Other$$aVisual field
000272137 650_2 $$2MeSH$$aHumans
000272137 650_2 $$2MeSH$$aFemale
000272137 650_2 $$2MeSH$$aMale
000272137 650_2 $$2MeSH$$aVirtual Reality
000272137 650_2 $$2MeSH$$aGlaucoma: physiopathology
000272137 650_2 $$2MeSH$$aVisual Acuity: physiology
000272137 650_2 $$2MeSH$$aMiddle Aged
000272137 650_2 $$2MeSH$$aVisual Fields: physiology
000272137 650_2 $$2MeSH$$aAged
000272137 650_2 $$2MeSH$$aSpatial Navigation: physiology
000272137 650_2 $$2MeSH$$aCase-Control Studies
000272137 7001_ $$0P:(DE-2719)9003189$$aStolle, Francie$$b1$$udzne
000272137 7001_ $$0P:(DE-2719)9002387$$aBernard, Matthieu$$b2$$udzne
000272137 7001_ $$aAl-Nosairy, Khaldoon O$$b3
000272137 7001_ $$0P:(DE-2719)2810583$$aWolbers, Thomas$$b4$$udzne
000272137 7001_ $$aHoffmann, Michael B$$b5
000272137 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/s41598-024-72040-8$$gVol. 14, no. 1, p. 21320$$n1$$p21320$$tScientific reports$$v14$$x2045-2322$$y2024
000272137 8564_ $$uhttps://pub.dzne.de/record/272137/files/DZNE-2024-01132%20SUP.pdf
000272137 8564_ $$uhttps://pub.dzne.de/record/272137/files/DZNE-2024-01132.pdf$$yOpenAccess
000272137 8564_ $$uhttps://pub.dzne.de/record/272137/files/DZNE-2024-01132%20SUP.pdf?subformat=pdfa$$xpdfa
000272137 8564_ $$uhttps://pub.dzne.de/record/272137/files/DZNE-2024-01132.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000272137 909CO $$ooai:pub.dzne.de:272137$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000272137 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)9002130$$aExternal Institute$$b0$$kExtern
000272137 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)9003189$$aExternal Institute$$b1$$kExtern
000272137 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9002387$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b2$$kDZNE
000272137 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810583$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b4$$kDZNE
000272137 9131_ $$0G:(DE-HGF)POF4-353$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vClinical and Health Care Research$$x0
000272137 9141_ $$y2024
000272137 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000272137 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bSCI REP-UK : 2022$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2023-04-12T15:11:06Z
000272137 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2023-04-12T15:11:06Z
000272137 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000272137 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)1150$$2StatID$$aDBCoverage$$bCurrent Contents - Physical, Chemical and Earth Sciences$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2023-08-24
000272137 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-24
000272137 9201_ $$0I:(DE-2719)1310002$$kAG Wolbers$$lAging, Cognition and Technology$$x0
000272137 980__ $$ajournal
000272137 980__ $$aVDB
000272137 980__ $$aUNRESTRICTED
000272137 980__ $$aI:(DE-2719)1310002
000272137 9801_ $$aFullTexts