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@MISC{Gloeckner:272966,
author = {Gloeckner, Christian Johannes},
title = {{D}ataset: {A}lpha{F}old3 model of {G} nucleotide-bound
{LRRK}2 phospho-{T}1343, v1},
publisher = {Zenodo},
reportid = {DZNE-2024-01345},
year = {2024},
abstract = {AlphaFold3 model of LRRK2-pT1343 either bound to GDP/Mg or
GTP/Mg. Using AlphaFold3 (Abramson et al., 2024), we modeled
and compared the GDP vs the GTP-state of phospho-T1343
LRRK2. Interestingly, the AlphaFold3 model suggests, that
the phosphate group of the pT1343 residue is orientated
inwards thereby substituting the gamma phosphate of the GTP
in the GDP-bound state of LRRK2. This finding is in well
agreement with MD simulations published recently (Stormer et
al., 2023).},
keywords = {structural modeling (Other) / LRRK2 (Other)},
cin = {AG Gloeckner},
cid = {I:(DE-2719)1210007},
pnm = {352 - Disease Mechanisms (POF4-352)},
pid = {G:(DE-HGF)POF4-352},
typ = {PUB:(DE-HGF)32},
doi = {10.5281/zenodo.11242230},
url = {https://pub.dzne.de/record/272966},
}