TY  - JOUR
AU  - Walter, Uwe
AU  - Loewenbrück, Kai F
AU  - Dodel, Richard
AU  - Storch, Alexander
AU  - Trenkwalder, Claudia
AU  - Höglinger, Günter
TI  - Systematic review-based guideline 'Parkinson's disease' of the German Society of Neurology: diagnostic use of transcranial sonography.
JO  - Journal of neurology
VL  - 271
IS  - 12
SN  - 0367-004X
CY  - Heidelberg
PB  - Springer
M1  - DZNE-2024-01374
SP  - 7387 - 7401
PY  - 2024
AB  - Transcranial brain parenchyma sonography (TCS) has been recommended as a tool for the early and differential diagnosis of Parkinson's disease (PD) in German and European clinical guidelines. Still, the brain structures to be examined for the diagnostic questions and the requirements for being a qualified investigator were not specified in detail. These issues have now been addressed in the 2023 update of the clinical guideline on PD by the German Society of Neurology (DGN).The recommendations were based on a systematic literature review following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.Three diagnostic questions were defined: (1) What is the accuracy of TCS in the differential diagnosis of PD versus atypical and secondary Parkinsonian syndromes? (2) What is the accuracy of TCS in the differential diagnosis of PD versus essential tremor? (3) What is the accuracy of TCS in the diagnosis of PD in persons with typical early symptoms, compared with the diagnosis established by clinical follow-up? The brain structures to be assessed and the level of recommendation were formulated for these questions. The training requirements for being regarded as qualified TCS investigator were stipulated by the responsible medical societies (German Society of Ultrasound in Medicine, DEGUM; German Society for Clinical Neurophysiology and Functional Imaging, DGKN). Finally, the recommendations for these diagnostic questions reached strong consensus (each ≥ 97
KW  - Humans
KW  - Parkinson Disease: diagnostic imaging
KW  - Parkinson Disease: diagnosis
KW  - Ultrasonography, Doppler, Transcranial: standards
KW  - Ultrasonography, Doppler, Transcranial: methods
KW  - Neurology: standards
KW  - Germany
KW  - Societies, Medical: standards
KW  - Practice Guidelines as Topic: standards
KW  - Diagnosis, Differential
KW  - Essential tremor (Other)
KW  - Neuroimaging (Other)
KW  - Parkinsonism (Other)
KW  - Parkinson’s disease (Other)
KW  - Systematic review (Other)
KW  - Transcranial ultrasound (Other)
LB  - PUB:(DE-HGF)16
C2  - pmc:PMC11588812
C6  - pmid:38963440
DO  - DOI:10.1007/s00415-024-12502-1
UR  - https://pub.dzne.de/record/273015
ER  -