Home > Publications Database > Systematic review-based guideline 'Parkinson's disease' of the German Society of Neurology: diagnostic use of transcranial sonography. > print

001     273015
005     20250127091714.0
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024 7 _ |a 10.1007/s00415-024-12502-1
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024 7 _ |a 0367-004X
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024 7 _ |a 0012-1037
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024 7 _ |a 1432-1459
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037 _ _ |a DZNE-2024-01374
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Walter, Uwe
|0 P:(DE-2719)9000336
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245 _ _ |a Systematic review-based guideline 'Parkinson's disease' of the German Society of Neurology: diagnostic use of transcranial sonography.
260 _ _ |a Heidelberg
|c 2024
|b Springer
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520 _ _ |a Transcranial brain parenchyma sonography (TCS) has been recommended as a tool for the early and differential diagnosis of Parkinson's disease (PD) in German and European clinical guidelines. Still, the brain structures to be examined for the diagnostic questions and the requirements for being a qualified investigator were not specified in detail. These issues have now been addressed in the 2023 update of the clinical guideline on PD by the German Society of Neurology (DGN).The recommendations were based on a systematic literature review following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.Three diagnostic questions were defined: (1) What is the accuracy of TCS in the differential diagnosis of PD versus atypical and secondary Parkinsonian syndromes? (2) What is the accuracy of TCS in the differential diagnosis of PD versus essential tremor? (3) What is the accuracy of TCS in the diagnosis of PD in persons with typical early symptoms, compared with the diagnosis established by clinical follow-up? The brain structures to be assessed and the level of recommendation were formulated for these questions. The training requirements for being regarded as qualified TCS investigator were stipulated by the responsible medical societies (German Society of Ultrasound in Medicine, DEGUM; German Society for Clinical Neurophysiology and Functional Imaging, DGKN). Finally, the recommendations for these diagnostic questions reached strong consensus (each ≥ 97%) of the guideline committee. Here, the details of review and recommendations are presented.The updated guideline clarifies the diagnostic uses and limitations of TCS in PD.
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650 _ 7 |a Essential tremor
|2 Other
650 _ 7 |a Neuroimaging
|2 Other
650 _ 7 |a Parkinsonism
|2 Other
650 _ 7 |a Parkinson’s disease
|2 Other
650 _ 7 |a Systematic review
|2 Other
650 _ 7 |a Transcranial ultrasound
|2 Other
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Parkinson Disease: diagnostic imaging
|2 MeSH
650 _ 2 |a Parkinson Disease: diagnosis
|2 MeSH
650 _ 2 |a Ultrasonography, Doppler, Transcranial: standards
|2 MeSH
650 _ 2 |a Ultrasonography, Doppler, Transcranial: methods
|2 MeSH
650 _ 2 |a Neurology: standards
|2 MeSH
650 _ 2 |a Germany
|2 MeSH
650 _ 2 |a Societies, Medical: standards
|2 MeSH
650 _ 2 |a Practice Guidelines as Topic: standards
|2 MeSH
650 _ 2 |a Diagnosis, Differential
|2 MeSH
700 1 _ |a Loewenbrück, Kai F
|b 1
700 1 _ |a Dodel, Richard
|b 2
700 1 _ |a Storch, Alexander
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700 1 _ |a Trenkwalder, Claudia
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700 1 _ |a Höglinger, Günter
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700 1 _ |a Group, German Parkinson Guideline
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773 _ _ |a 10.1007/s00415-024-12502-1
|g Vol. 271, no. 12, p. 7387 - 7401
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|p 7387 - 7401
|t Journal of neurology
|v 271
|y 2024
|x 0367-004X
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